Hematopathology

The Hematopathology Laboratory and the Division of Hematopathology offers diagnostic consultative services and a comprehensive testing menu for the evaluation of hematologic disorders. The Division of Hematopathology consists of nationally and internationally known experts whose expertise spans many different subspecialties of hematopathology including flow cytometry, immunohistochemistry, cytogenetics, coagulation, and molecular diagnostics. An integrated approach is utilized to provide clients with services ranging from test interpretation and selection to a comprehensive histomorphologic diagnosis.

For information concerning consultation, please call (801) 581-5854. Consultations can be sent directly to:

ARUP Laboratories
Specimen Processing
500 Chipeta Way
Salt Lake City, Utah 84108

Phone: (801) 581-5854
Fax: 801-585-3831

Please include pertinent clinical history and  surgical pathology/Hematopathology and flow cytometry report(s).

Test # Test Name Test Keywords Additional Information
Consultation, Hematopathology Kidney biopsy, light microscopy, immunofluorescence, electron microscopy, Renal disease, chronic kidney disease, hematuria, Hematopathology, hematologic
0049010 Acid Hemolysin (Ham Test)Paroxysmal Nocturnal Hemoglobinuria (PNH) Paroxysmal Nocturnal Hemoglobinuria (PNH) PNH testing with Flaer by flow cytometry may be a better test to evaluate for PNH
2002647 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Adult FISH A ALL, B-Cell Lymphoma, MYC BCR-ABL1, MLL, IGH@, TCF3, E2A
2002719 Acute Lymphocytic Leukemia (ALL) Panel by FISH, Pediatric FISH P ALL, Oncology, Bone Marrow , B-Cell Lymphoma, childhood, child, children, CEP4, CEP10, BCR-ABL1 MLL, ETV6-RUNX1, TEL-AML1
2002653 Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS), or Therapy-Related AML, by FISH F TAML MDS, Myelodysplastic syndrome, Acute Myeloid Leukemia, EGR1, D7S486, MLL
2002384 Acute Myelogenous Leukemia Panel by FISH FISH AML P, Acute Myeloid Leukemia, AML, Myeloproliferative, MPD, PML-RARA, RUNX1T1-RUNX1, ETO-AML1, CBFB, MLL
0092099 B-Cell CD20 Expression B-cell lymphomas, B-cell leukemias
2006193 B-Cell Clonality Screening (IgH and IgK) by PCR B-Cell Lymphomas, B-cell Leukemias Additional Technical Information
0055553 BCR-ABL, t(9;22) Translocation Qualitative by RT-PCR Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL)
0040138 BCR-ABL1 Kinase Domain Mutation Analysis Chronic Myelogenous Leukemia (CML), Acute Lymphoblastic Leukemia (ALL), Tumor Markers Additional Technical Information
2005017 BCR-ABL1, Major (p210), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML) Additional Technical Information
2005016 BCR-ABL1, Minor (p190), Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML) Additional Technical Information
2005010 BCR-ABL1, Qualitative with Reflex to BCR-ABL1 Quantitative Chronic Myelogenous Leukemia (CML)
2004924 BCR-ABL1, T315I Mutation Detection, Quantitative Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia Additional Technical Information
0055691 BIRC2-MALT1 (API2-MALT1) Translocation, t(11;18) by RT-PCR Marginal Zone B-Cell Lymphoma, Mucosa Associated Lymphoid Tumor (MALT) lymphoma, Tumor Markers
2007130 Bone Marrow, Chromosome Analysis with Reflex to Genomic Microarray ALL, Bcell, B-cell, b cell, T-cell, Tcell, T Cell, B-ALL, CDKN2A/B, BTG1, IKZF1, EBF1, UPD 9p, Myelodysplastic, MDS, Myeloproliferative, MPD, 5q-; -7 or 7q-,+8; 20q-, LOH, UPD 7q, UPD 11q, UPD 17p, CLL, P53, Chronic lymphocytic leukemia
2007132 BRAF V600E Mutation Detection in Hairy Cell Leukemia by Real-Time PCR, Quantitative Additional Technical Information
0092209 CBFB-MYH11, inv(16) by RT-PCR Acute Myeloid Leukemia (AML), Tumor Markers Additional Technical Information
2004247 CEBPA Mutation Detection Acute Myelogenous Leukemia (AML) Additional Technical Information
2002292 Chromosome Analysis, Bone Marrow Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002290 Chromosome Analysis, Leukemic Blood Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, MDS, B-cell lymphomas, T-cell lymphomas
2002295 Chromosome FISH, CLL Panel FISH CLLP, Chronic Lymphocytic Leukemia, CLL, Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers, ATM, D12Z3, D13S319, TP53, p53
2002298 Chromosome FISH, Interphase Oncology, Bone Marrow, Ewing Sarcoma, Neuroblastoma, Myelodysplastic, MDS, Chronic Lymphocytic Leukemia (CLL), Sarcoma, Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML), Tumor Markers, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), Plasma Cell Dyscrasias, Lymphoma Phenotyping, B-Cell Lymphomas Please specify which FISH probe you wish to order.
2002378 Eosinophilia Panel by FISH FISH EOS P, Mast Cell Disease, Eosinophilic Diseases, Acute Myeloid Leukemia (AML), Myeloproliferative Neoplasms (MPN), PDGFRA-CHIC2-FIP1L1, PDGFRB, FGFR1, CBFB
2002902 Epstein-Barr Virus (EBV) by in situ Hybridization, Paraffin Epstein-Barr Virus (EBV), Nasopharyngeal carcinoma, NK/ T-cell lymphomas, B-cell lymphomas, Post transplant lymphoproliferative disorders, Tumor Markers, ISH, Nasopharyngeal nonkeratinizing undifferentiated carcinoma, Nasal type NK/T-cell lymphoma
0049050 Esterase Stain, Nonspecific Acute Myeloid Leukemia (AML)
0056008 ETV6-RUNX1 (TEL-AML1) Translocation, t(12;21) by RT-PCR Acute Lymphoblastic Leukemia (ALL), Tumor Markers Additional Technical Information
2005400 FLT3 Mutation Detection by PCR Acute Myeloid Leukemia Additional Technical Information
0049090 Heinz Body Stain Unstable Hemoglobinopathies, Hemolytic Anemias
0055616 IGH-BCL2 (BCL-2/JH) Translocation, t(14;18) by PCR Lymphoma Phenotyping, Follicular lymphoma, Diffuse large B-cell lymphoma, B-Cell Lymphomas, Tumor Markers
2001536 IGH-BCL2 Fusion, t(14;18) by FISH for Detection in Follicular Lymphoma B-Cell Lymphomas, Follicular lymphoma, Diffuse large B-cell lymphoma, FISH
0055557 IGH-CCND1 (BCL-1/JH) Translocation, t(11;14) by PCR Mantle cell Lymphoma , B-Cell Lymphomas, Tumor Markers
2007226 IGH-CCND1 Fusion, t(11;14) by FISH Mantle cell lymphoma, B-Cell Lymphomas, Plasma cell dyscrasias, Tumor Markers
2001538 IGH-MYC Fusion t(8;14) by FISH for Detection in Burkitt Lymphoma Burkitt lymphoma, B-Cell Lymphomas Additional Technical Information
0040227 IGHV Mutation Analysis by Sequencing Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Additional Technical Information
0049110 Iron Stain Bone marrows, Blood smears
2002357 JAK2 Exon 12 Mutation Analysis by PCR Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0051245 JAK2 Gene, V617F Mutation, Qualitative Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0040168 JAK2 Gene, V617F Mutation, Quantitation Myeloproliferative Neoplasms (MPN), Tumor Markers Additional Technical Information
0055629 Kaposi Sarcoma-Associated Herpesvirus/Human Herpesvirus 8 Hematologic Cancer, Kaposi Sarcoma, Castleman disease, Tumor Markers
2002888 Kappa/Lambda Light Chain Panel by in situ Hybridization, Paraffin Plasma cell dyscrasias, B-cell lymphomas, ISH More ISH testing
2004519 Ki-67, MIB1, by Immunohistochemistry B-cell Lymphomas, T-Cell Lymphomas, Tumor marker, astrocytoma Stain and return service only
0040137 KIT (D816V) Mutation by PCR Mast Cell Disease, C-KIT, CKIT Technical Bulletin
2002437 KIT Mutations in AML by Fragment Analysis and Sequencing Acute Myeloid Leukemia (AML), C-KIT, CKIT Additional Technical Information
2008003 Leukemia/Lymphoma Phenotyping by Flow Cytometry
2007131 Leukemic Blood, Chromosome Analysis with Reflex to Genomic Microarray
0049000 Leukocyte Alkaline Phosphatase Chronic Myelogenous Leukemia (CML), Hematologic Cancer
2002650 Lymphoma (Aggressive) Panel by FISH FISH ALYMP, Lymphoma Phenotyping, B-Cell Lymphomas, Lymphoproliferative Disorders (LPD), BCL6, MYC, IGH@/BCL2
0055655 Methylenetetrahydrofolate Reductase (MTHFR) 2 Mutations MTHFR PCR, Thrombophilia, methotrexate sensitivity, cardiovascular, C677T, A1298C
0050446 MLL-AFF1 (MLL-AF4) Translocation, t(4;11) by RT-PCR Acute Lymphoblastic Leukemia (ALL), Tumor Markers
2005545 MPL codon 515 Mutation Detection by Pyrosequencing, Quantitative Myeloproliferative Neoplasms, MPN Additional Technical Information
2002294 Multiple Myeloma Panel by FISH FISH MMP, Plasma Cell Dyscrasias, CKS1B, ASS1, CCND1-IGH@, IGH@, PML, TP53, FGFR3-IGH@, IGH@-MAF
2002345 MYC (8q24) Gene Rearrangement by FISH Burkitt lymphomas, B-Cell Lymphomas, Double Hit lymphomas, Tumor Markers Additional Technical Information
2002709 Myelodysplastic Syndrome (MDS) Panel by FISH FISH MDS P, Myelodysplastic Syndrome (MDS), EGR1, D7S486, CEP8, D20S108
0049030 Myeloperoxidase Stain Acute Myeloid Leukemia (AML), congenital deficiencies
2002360 Myeloproliferative Disorders Panel by FISH FISH MPD P, Chronic Myelogenous Leukemia (CML), Myeloproliferative Neoplasms (MPN), PDGFRα-CHIC2-FIP1L1, PDGFRa-CHIC2-FIP1L1, PDGFRβ, FGFR1, ABL1-BCR
2007418 Myeloproliferative Neoplasms Reflex Panel Additional Technical Information
0040174 NPM1 Mutation by PCR and Fragment Analysis Acute Myeloid Leukemia (AML) Additional Technical Information
2002257 Osmotic Fragility, Erythrocyte Hemolytic Anemias
0049045 Periodic Acid Schiff Stain Acute Myeloid Leukemia (AML)
2002363 PML-RARA Translocation by FISH FISH PML, Acute Myeloid Leukemia (AML), Acute Promyelocytic Leukemia (APL), Tumor Markers
2002871 PML-RARA Translocation, t(15;17) by RT-PCR, Quantitative Acute Myelogenous Leukemia (AML), Acute Promyelocytic Leukemia (APL) Additional Technical Information
0050444 RUNX1-RUNX1T1 (AML1-ETO) Translocation, t(8;21) by RT-PCR Acute Myeloid Leukemia (AML), Tumor Markers
0049180 Sezary Cell Exam Sézary Syndrome, Mycosis Fungoides
0093199 T-Cell Clonality by Flow Cytometry Analysis of TCR V-Beta
0055567 T-Cell Clonality Screening by PCR Hematologic Cancer, Sézary Syndrome, T-Cell Lymphomas, Lymphoma Phenotyping
0049060 Tartrate Resistant Acid Phosphatase Stain Hairy cell leukemia
0055346 TCF3-PBX1 (E2A-PBX1) Translocation, t(1;19) by RT-PCR Acute Lymphoblastic Leukemia (ALL), Tumor Markers Additional Technical Information
2005766 WT1 Mutation Detection by Sequencing AML Additional Technical Information
0092392 ZAP-70 Analysis by Flow Cytometry Chronic Lymphocytic Leukemia (CLL), Lymphoma Phenotyping, B-Cell Lymphomas, Tumor Markers Technical Bulletin