ARUP's Laboratory Test Directory

von Willebrand Multimeric Panel : 0030002

Mnemonic: VW MUL PAN

Ordering Recommendation: Not recommended for initial screening except in suspected cases of acquired von Willebrand disease (vWD) or high suspicion of vWD. Preferred initial test is von Willebrand Panel with Reflex to von Willebrand Multimeric Analysis (2003387).
Methodology: Electrophoresis/Western Blot/Clotting/Microlatex Particle-Mediated Immunoassay/Platelet Agglutination
Performed: Mon-Sat
Reported: 1-11 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 3 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1.5 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum. Hemolyzed or non-frozen specimens.

Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: Unacceptable; Frozen at -20°C: 3 months; Frozen at -70°C: 6 months
Reference Interval:
 
Test Number Components Reference Interval
 von Willebrand Multimeric  Normal
0030095Factor VIII, Activity 0-6 years: 56-191%
7-9 years: 76-199%
10-11 years: 80-209%
12-13 years: 72-198%
14-15 years: 69-237%
16-17 years: 63-221%
18 years and older: 56-191%
0030285von Willebrand Factor Antigen 0-6 years: 52-214%
7-9 years: 62-180%
10-11 years: 63-189%
12-13 years: 60-189%
14-15 years: 57-199%
16-17 years: 50-205%
18 years and older: 52-214%
0030250von Willebrand Factor Activity (Ristocetin Cofactor) 0-6 years: 51-215%
7-9 years: 52-176%
10-11 years: 60-195% 
12-13 years: 50-184%
14-15 years: 50-203 %
16-17 years: 49-204%
18 years and older: 51-215%

CPT Code(s): 85247; 85240; 85246; 85245