ARUP's Laboratory Test Directory

von Willebrand Factor Activity (Ristocetin Cofactor) : 0030250

Mnemonic: RCF

Ordering Recommendation: Order in conjunction with von Willebrand Factor Antigen (0030285) and Factor VIII Activity (0030095) as part of initial workup of suspected von Willebrand disease.
Methodology: Platelet Agglutination
Performed: Mon-Sat
Reported: 1-3 days
Specimen Required: Collect: Lt. blue (sodium citrate). Refer to Specimen Handling at aruplab.com for hemostasis/thrombosis specimen handling guidelines.

Specimen Preparation: Transfer 1.5 mL platelet-poor plasma to an ARUP Standard Transport Tube. (Min: 1 mL)

Storage/Transport Temperature: CRITICAL FROZEN. Separate specimens must be submitted when multiple tests are ordered.

Unacceptable Conditions: Serum. Hemolyzed or non-frozen specimens.

Stability (collection to initiation of testing): Ambient: 4 hours; Refrigerated: Unacceptable; Frozen: at -20°C: 3 months; Frozen at -70°C: 6 months

Reference Interval:
0-6 years: 51-215%
7-9 years: 52-176%
10-11 years: 60-195% 
12-13 years: 50-184%
14-15 years: 50-203 %
16-17 years: 49-204%
18 years and older: 51-215%
CPT Code(s): 85245
Cross References: RCF, Ristocetin Cofactor, Plasma, von Willebrand Factor (vWF) Activity, von Willebrand Factor Antigen, Plasma