p53 with Interpretation by Immunohistochemistry
:0049250
Mnemonic: P53 IP
Methodology:
Immunohistochemistry
Performed:
Mon-Fri
Reported:
1-5 days
Specimen Required:
Collect: Tumor tissue.
Specimen Preparation: Formalin fix (10 percent neutral buffered formalin is preferred) and paraffin embed specimen. Protect paraffin block and / or slides from excessive heat. Transport tissue block or 5 unstained (3-5 micron thick sections), positively charged slides in a tissue transport kit (ARUP supply #47808) available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. (Min. 3 slides).If sending precut slides, do not oven bake.
Storage/Transport Temperature: Room temperature or refrigerated. Ship in cooled container during summer months.
Remarks: This test code includes pathologist interpretation. Include surgical pathology report. IMMUNOHISTOCHEMISTRY ORDERING AND SUBMISSION DETAILS: Submit electronic request. If you do not have electronic ordering capability, use an ARUP Immunohistochemistry Stain Form (#32978) with an ARUP client number. For additional technical details, please contact ARUP Client Services at (800) 522-2787.
Unacceptable Conditions: Paraffin block with no tumor tissue remaining; specimens fixed in B-5 or Bouin's fixative.
Stability (collection to initiation of testing): Ambient: Indefinitely; Refrigerated: Indefinitely; Frozen: Unacceptable
Reference Interval:
Negative : Less than 10% of nuclei stain Positive: Greater than or equal to 10% of nuclei stain
Interpretive Data:
Refer to report.
CPT Code(s):
88360
Cross References:
p53 Tumor Suppressor Protein (p53 Tissue Assay, Paraffin), Protein 53 (p53 Tissue Assay, Paraffin), Tumor Protein 53 (p53 Tissue Assay, Paraffin)
