ARUP's Laboratory Test Directory

Aspergillus Antibody by CF : 0050100

Mnemonic: ASPER

Methodology: Semi-Quantitative Complement Fixation
Performed: Sun-Sat
Reported: 1-3 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL) Parallel testing is preferred and convalescent specimens must be received within 30 days from receipt of the acute specimens. Mark specimens plainly as "acute" or "convalescent."

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Contaminated or severely lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
< 1:8
Interpretive Data: Cross-reactions with dimorphic fungi are not unusual with the genus Aspergillus. A negative test does not exclude infection, especially in immunocompromised patients. Best use of the test is with paired sera taken three weeks apart to detect a rise in titer against a single antigen.
Note: Negative fungal serology does not rule out the possibility of current infection.
CPT Code(s): 86606