ARUP's Laboratory Test Directory

Coccidioides Antibody by ID : 0050183

Mnemonic: COCCI-PPT

Methodology: Qualitative Immunodiffusion
Performed: Sun-Fri
Reported: 2-4 days
Specimen Required: Collect: Serum separator tube OR CSF.

Specimen Preparation: Transfer 0.5 mL serum OR CSF to an ARUP Standard Transport Tube (Min: 0.15 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Bloody or grossly hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
None detected.
Interpretive Data: Coccidioides infection is demonstrated by the detection of IgM antibody to the Immunodiffusion Tube Precipitin (IDTP) antigen. IgM antibody may be detected 1 to 3 weeks after the onset of primary infection and may suggest active or recent infection. IgM antibody is rarely detected 6 months after infection but may reappear with relapse and may persist in disseminated cases.

IgG antibody may also be demonstrated in response to the Immunodiffusion Complement Fixation (IDCF) antigen and may represent active or past infection. Negative fungal serology does not rule out current infection.
Note: This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens.
CPT Code(s): 86635
Cross References: Coccidioides Antibody (TP Antigen) (Coccidioides Ab by ID), Coccidioides Antibody (TP Antigen), Immunodiffusion (Coccidioides Ab by ID), Coccidioidomycosis IgG/IgM (Coccidioides Antibody by ID) , San Joaquin Fever Antibody (Coccidioides Antibody by ID) , Valley Fever (Coccidioides Antibody by ID)