ARUP's Laboratory Test Directory

Endomysial Antibody, IgA by IFA : 0050736

Mnemonic: EMAR TITER

Ordering Recommendation: Do not use in IgA-deficient individuals; acceptable single screening test for celiac disease. Acceptable follow-up test for weakly positive or negative tissue transglutaminase (tTG) IgA screen. Celiac Disease Reflexive Panel (0051065) or Tissue Transglutaminase (tTG) Antibody, IgA (0097709) testing is the preferred testing for screening at-risk patients for celiac disease who should undergo small bowel biopsy to confirm disease.
Methodology: Semi-Quantitative Indirect Fluorescent Antibody
Performed: Mon-Fri
Reported: 1-5 days
Specimen Required: Collect: Serum separator tube.

Specimen Preparation: Separate serum from cells ASAP. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.15 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma. Severely lipemic, contaminated, or hemolyzed specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid freeze/thaw cycles)

Reference Interval:
Less than 1:10
Interpretive Data: The endomysial antigen has been identified as the protein cross-linking enzyme known as tissue transglutaminase.
CPT Code(s): 86256