Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep(R))

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Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep®) : 0060750

Mnemonic: TP HPV-HI

Ordering Recommendation:	Order to detect high-risk HPV in cytology specimens collected in ThinPrep® preservative.
Methodology:	Qualitative Nucleic Acid Probe
Performed:	Sun-Sat
Reported:	Within 2 days
Specimen Required:	Patient Prep: Females should avoid high concentrations of antifungal cream, contraceptive jelly, or douche at time of collection. Collect: Cervical Brush in ThinPrep® transport Pap Test™ media. Specimen Preparation: Place each specimen in an individually sealed bag. (Min: 4 mL) Storage/Transport Temperature: Room temperature. Also acceptable: Refrigerated. Remarks: Specimen source required. Unacceptable Conditions: Specimens in any transport media other than indicated above. For specimens in ThinPrep® Test transport media, refer to ARUP test code 0060750. For cervical brush specimens in Digene Transport media, refer to ARUP test code 0065999. Stability (collection to initiation of testing): Ambient: 3 months; Refrigerated: 3 months; Frozen: Unacceptable

Reference Interval: Negative
Interpretive Data:	This test detects the high-risk HPV genotypes 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59 and 68 associated with cervical cancer and its precursor lesions. However, cross-reactions with other genotypes may occur. Results should be correlated with cytologic and histologic findings. Sensitivity may be affected by cellularity of specimen. This test is intended for medical purposes only and is not valid for the evaluation of suspected sexual abuse or for other forensic purposes. HPV testing should not be used for screening or management of atypical squamous cells of undetermined significance (ASCUS) in women under age 21.
CPT Code(s):	87621
Cross References:	Condyloma (Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep®)) , Genital Warts (Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep®) , HPV RNA, High Risk, E6/E7, TMA (Human Papillomavirus (HPV) DNA Probe, High Risk (ThinPrep(R)))