ARUP's Laboratory Test Directory

NMP22 (Temporary Referral as of 5/24/2013) : 0080281

Mnemonic: NMP22

Methodology: Quantitative Enzyme Immunoassay
Performed: Thu
Reported: 1-8 days
Specimen Required: Patient Prep: Testing with the Matritech NMP22® should not be performed on patients who have had a total cystectomy or an invasive procedure, such as cystoscopy or catheterization of the urethra, within five days.

Collect: Single void of urine between midnight and noon. Urine stabilization kit required (ARUP Supply #12594). Available online through eSupply using ARUP Connect™ or by contacting ARUP Client Services at (800) 522-2787. Immediately following collection, add urine to NMP22® Urine Stabilizer Vial.

Specimen Preparation: Immediately following collection, transfer 5 mL urine to NMP22® Urine Stabilizer Vial (ARUP Supply #12594). Available online through eSupply using ARUP Connect™ or contact ARUP Client Services at (800) 522-2787. Stabilized specimen should be blue/green in color.)

Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Urine not stabilized in NMP22® Urine Stabilizer Vial.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 72 hours; Frozen: 1 month

Reference Interval:
0.0-10.0 U/mL
Interpretive Data: The NMP22® assay is intended as an aid in the management of patients with transitional cell carcinoma of the urinary tract (TCC/UT).  It is used after surgical treatment to identify patients with residual or rapidly recurring TCC/UT.  Testing with the Matritech NMP22® should not be performed on patients who have had a total cystectomy or within five days of an invasive procedure, such as cystoscopy or catheterization of the urethra.

Values obtained with different assay methods should not be used interchangeably.  ARUP uses the Matritech NMP22® Test Kit which is an enzyme immunoassay (EIA) method.
CPT Code(s): 86316
Cross References: Bladder Tumor Associated Antigen (NMP22®) , Nuclear Matrix Protein (NMP22®)