ARUP's Laboratory Test Directory

Drug Screen 9 Panel, Serum or Plasma - Immunoassay Screen with Reflex to Mass Spectrometry Confirmation/Quantitation : 0092420

Mnemonic: DRUG SCRSP

Methodology: Qualitative Enzyme-Linked Immunosorbent Assay/ Quantitative Gas Chromatography-Mass Spectrometry/Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-2 days
Confirmation: 1-4 days
Specimen Required: Collect: Gray (sodium fluoride/potassium oxalate). Also acceptable: Plain red, green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Remove plasma from cells ASAP or within 2 hours of collection. Transfer 4 mL plasma to an ARUP Standard Transport Tube. (Min: 3 mL) Also acceptable: Serum.

Storage/Transport Temperature: Refrigerated.

Remarks: Cocaine and cocaethylene are more stable in fluoride-preserved plasma than serum.

Unacceptable Conditions: Specimens exposed to repeated freeze/thaw cycles. Separator tubes. Plasma or whole blood collected in lt. blue (sodium citrate).

Stability (collection to initiation of testing): After separation from cells: Ambient: 1 week; Refrigerated: 2 weeks; Frozen: 3 years

Reference Interval:
Drugs Covered and Cutoff Concentrations
Drugs/Drug Classes Screen
Amphetamines 30 ng/mL
Methamphetamine 30 ng/mL
Barbiturates 75 ng/mL
Benzodiazepines 75 ng/mL
Cannabinoids 30 ng/mL
Cocaine 30 ng/mL
Methadone 40 ng/mL
Opiates 30 ng/mL
Oxycodone 30 ng/mL
Phencyclidine 15 ng/mL
Propoxyphene 75 ng/mL

Interpretive Data: Drugs/Drug classes reported as "Positive" are automatically reflexed to mass spectrometry confirmation/quantitation. An unconfirmed positive immunoassay screen result may be useful for medical purposes but does not meet forensic standards. The absence of expected drug(s) and/or drug metabolite(s) may indicate non-compliance, inappropriate timing of specimen collection relative to drug administration, poor drug absorption, or limitations of testing. The concentration at which the screening test can detect a drug or metabolite varies within a drug class. Specimens for which drugs or drug classes are detected by the screen are automatically reflexed to a second, more specific technology (GC/MS and/or LC-MS/MS). The concentration value must be greater than or equal to the cutoff to be reported as positive. Interpretive questions should be directed to the laboratory.

For medical purposes only; not valid for forensic use.

See Compliance Statement B: www.aruplab.com/CS
Note: Screen-positive specimens are automatically confirmed by GC/MS and/or LC-MS/MS; additional charges may apply.
CPT Code(s): 80101 x9 (HCPCS:G0431); if positive add appropriate CPT code(s): 82542; 82520; 83925; 83992; 82145; 82205; 80154; 83840; 83925
Cross References: Pain Management (Drugs of Abuse 9 Panel, Serum or Plasma - Screen with Reflex to Confirmation/Quantitation)