#ExistInterpData>A CD4/CD8 ratio greater than 3.5 is suggestive of sarcoidosis. If the CD4/CD8 ratio is greater than 5.0 and clinical and radiographic findings are compatible with sarcoidosis, some institutions accept a diagnosis of sarcoidosis even with a negative biopsy. In extrinsic allergic alveolitis (EAA), the CD4/CD8 ratio is decreased due to a relative increase in the CD8 positive T-cells.
The performance characteristics of this test were determined by ARUP Laboratories, Inc.
See Compliance Statement B: www.aruplab.com/CS
||This test is designed for enumerating the percent of T-Cell lymphocyte subsets in BAL. Cells from the BAL are added to fluorochrome-labeled antibodies that bind specifically to cell surface antigens on lymphocytes. The CD4/CD8 ratio is calculated by dividing the CD4 percent by the CD8 percent.
||86356; 86356; 86356
||BAL for CD4/CD8 Ratio (Lymphocyte Subset Panel 4 - T-Cell Subsets Percents and Ratio, Bronchoalveolar Lavage)
, Bronch Wash for CD4:CD8 Ratio (Lymphocyte Subset Panel 4 - T-Cell Subsets Percents and Ratio, Bronchoalveolar Lavage)