ARUP's Laboratory Test Directory

Jo-1 Antibody, IgG : 0099592

Mnemonic: ANTI-JO

Methodology: Semi-Quantitative Multiplex Bead Assay
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Serum separator tubes.

Specimen Preparation: Separate serum from cells ASAP or within 2 hours of collection. Transfer 1 mL serum to an ARUP Standard Transport Tube. (Min: 0.2 mL)

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Plasma or other body fluids.

Stability (collection to initiation of testing): After separation from the cells: Ambient: 48 hours; Refrigerated: 2 weeks; Frozen: 1 year (avoid repeated freeze/thaw cycles)
Reference Interval:
29 AU/mL or less: Negative
30-40 AU/mL: Equivocal
41 AU/mL or greater: Positive
Note: Presence of Jo-1 antibody is found in patients with pure polymyositis, pure dermatomyositis, or myositis associated with another rheumatic disease or with interstitial lung disease.
CPT Code(s): 86235
Cross References: Anti-Jo-1 Antibody (Jo-1 Antibody, IgG), Histidyl-tRNA Synthetase Antibodies (Jo-1 Antibody, IgG), Synthetase Antibody (Jo-1 Antibody, IgG)