ARUP's Laboratory Test Directory

Chromosome FISH, Metaphase : 2002299
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Time Sensitive
[ image for: Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies]
Patient History for Pediatric/Adult Cytogenetic (Chromosome) Studies


Mnemonic: CHR FISHM

Methodology: Fluorescence in situ Hybridization
Performed: Sun-Sat
Reported: 3-10 days
Specimen Required: Collect: Green (sodium heparin). Also acceptable: Non-diluted bone marrow aspirate collected in a heparinized syringe.
Other specimen types may be acceptable, contact the Cytogenetics Laboratory for specific specimen collection and transportation instructions.

Specimen Preparation: Transport 5 mL whole blood (Min: 2 mL). OR transfer 3 mL bone marrow to a green (sodium heparin) (Min: 1 mL).

Storage/Transport Temperature: Room temperature.

Remarks: It is recommended that all FISH studies be done in conjunction with routine cytogenetic analysis. (Refer to appropriate Chromosome Analysis test for order instructions). If FISH only is requested, please submit a copy of previous cytogenetics report.
If cell pellets or dropped cytogenetic slides are submitted, processing fee will not apply.
This test must be ordered using Cytogenetic test request form #43097 or through your ARUP interface. Submit the Patient History for Cytogenetic (Chromosome) Studies form with the electronic packing list (available at http://www.aruplab.com/genetics/forms.php).

Unacceptable Conditions: Frozen specimens. Paraffin-embedded specimens. Clotted specimens.

Stability (collection to initiation of testing): Ambient: 48 hours; Refrigerated: 48 hours; Frozen: Unacceptable
Reference Interval:
By report
Interpretive Data: Counseling and informed consent are recommended for genetic testing. Consent forms are available online at www.aruplab.com.

See Compliance Statement A: www.aruplab.com/CS
Note: Time required for culture as well as testing can vary depending on specimen type and probes ordered.

Please indicate names of probes requested. Molecular Cytogenetics (FISH) Probe menu is available at http://www.aruplab.com/Lab-Tests/Genetics/cytogenetics.jsp 
Contact ARUP Genetics Processing at extension 3301 to add a probe to a current specimen.

A processing fee will be charged if this procedure is canceled at the client's request, after the test has been set up, or if the specimen integrity is inadequate to allow culture growth. The fee will vary based on specimen type.
CPT Code(s): 88271; 88273; 88291
Cross References: 15q11.2-13 (Chromosome FISH, Metaphase), 17p11.2 (Chromosome FISH, Metaphase), 17p13.3 (Chromosome FISH, Metaphase), 1p36 Deletion Syndrome (Chromosome FISH, Metaphase), 22q Ter Deletion Syndrome (Chromosome FISH, Metaphase), 22q11.2 (Chromosome FISH, Metaphase), 22q13.3 (Chromosome FISH, Metaphase), 4p16.3 (Chromosome FISH, Metaphase), 5p15.2 (Chromosome FISH, Metaphase), 7q11.23 (Chromosome FISH, Metaphase), Angelman Syndrome/Prader-Willi Syndrome (Chromosome FISH, Metaphase), CEB 108/T7/CDC2LC (p58) (Chromosome FISH, Metaphase), Cri-Du-Chat (Chromosome FISH, Metaphase), D15S10 (Chromosome FISH, Metaphase), D15S11,D15S0 (Chromosome FISH, Metaphase), D5S23/D5S721 (Chromosome FISH, Metaphase), DiGeorge Syndrome/VCF (Velocardiofacial Syndrome) (Chromosome FISH, Metaphase), dup15q11.2-12 (Chromosome FISH, Metaphase), ELN/LIMK1/D7S613 (Chromosome FISH, Metaphase), LIS1 (Chromosome FISH, Metaphase), Male Detection (Chromosome FISH, Metaphase), Miller-Dieker Syndrome (Lisencephaly) (Chromosome FISH, Metaphase), OCTN2 (Chromosome FISH, Metaphase), q22 (Chromosome FISH, Metaphase), SHMT1/TOP3/FL11/LLGL1 (Chromosome FISH, Metaphase), SHOX (Chromosome FISH, Metaphase), Smith-Magenis Syndrome (Chromosome FISH, Metaphase), SRY (Chromosome FISH, Metaphase), Steroid Sulfatase Deficiency (Chromosome FISH, Metaphase), STS (Chromosome FISH, Metaphase), TUPLE-1 (HIRA) (Chromosome FISH, Metaphase), VCF Syndrome (Chromosome FISH, Metaphase), WHSC1 (Chromosome FISH, Metaphase), Williams (Elastin-Williams) Syndrome (Chromosome FISH, Metaphase), Wolf-Hirschhorn Syndrome (Chromosome FISH, Metaphase), Xp22 (Chromosome FISH, Metaphase), Yp11.3 (Chromosome FISH, Metaphase)