ARUP's Laboratory Test Directory

BCR-ABL1, T315I Mutation Detection, Quantitative : 2004924
[ image for: Time Sensitive]
Time Sensitive
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Additional Technical Information


Mnemonic: ABL T315I

Ordering Recommendation: Order this test only for patients known to have a BCR-ABL1 translocation.
Methodology: Reverse Transcription Polymerase Chain Reaction/Pyrosequencing
Performed: RNA isolation: Sun-Sat
Assay: Varies
Reported: 10-12 days
Specimen Required: Collect: Lavender (EDTA) or bone marrow (EDTA).

Specimen Preparation: Transport 5 mL whole blood or 3 mL bone marrow. (Min: 1 mL whole blood or 1 mL bone marrow) Specimens must be received within 48 hours of collection due to lability of RNA.

Storage/Transport Temperature: Refrigerated.

Unacceptable Conditions: Serum or plasma. Specimens collected in anticoagulants other than EDTA. Frozen specimens. Clotted or severely hemolyzed specimens.

Stability (collection to initiation of testing): Ambient: 1 hour; Refrigerated: 48 hours; Frozen: Unacceptable
Interpretive Data: Refer to report.

See Compliance Statement B: www.aruplab.com/CS
Note: This assay will only detect the BCR-ABL1 T315I mutation. For a more comprehensive ABL1 mutation detection test, please order BCR-ABL1 Kinase Domain Mutation Analysis (ARUP test code 0040138).
CPT Code(s): 81401, G0452