ARUP's Laboratory Test Directory

Methylmalonic Acid, Serum or Plasma (Metabolic Disorders) : 2005255

Mnemonic: MMA METD

Ordering Recommendation: This test is used to evaluate and monitor methylmalonic acidemia.
Methodology: Quantitative Liquid Chromatography-Tandem Mass Spectrometry
Performed: Sun-Sat
Reported: 1-2 days
Specimen Required: Collect: Plain red or serum separator tube. Also acceptable: Green (sodium heparin), lavender (EDTA), or pink (K2EDTA).

Specimen Preparation: Centrifuge and remove serum or plasma from cells within 2 hours of collection. Immediately transfer 2 mL serum or plasma to an ARUP Standard Transport Tube and
refrigerate or freeze. (Min: 1 mL)


Storage/Transport Temperature: Frozen.

Unacceptable Conditions: Room temperature specimens. Grossly hemolyzed or lipemic specimens.

Stability (collection to initiation of testing): After separation from cells: Ambient: Unacceptable; Refrigerated: 4 days; Frozen: 1 month

Reference Interval:
Effective July 18, 2011

0.00-0.40 µmol/L
Interpretive Data:

See Compliance Statement B: www.aruplab.com/CS
CPT Code(s): 83921
Cross References: MMA (Methylmalonic Acid, Serum or Plasma (Metabolic Disorders))