Fungal Serology

Test # Test Name   Specimen Type Fungal Yeast Reported Analytical Method Description
0050164 Fungal Antibodies by Immunodiffusion Fungal Panel Serum Aspergillus spp. Abs, Precipitin
Blastomyces dermatitidis Abs, Precipitin
Histoplasma spp. Abs, Precipitin
Coccidioides immitis Abs, Precipitin
Qualitative Immunodiffusion Not recommended. Refer to individual fungus-related tests appropriate to patient exposure.
3000230 Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion, CSF Fungal Panel CSF Aspergillus Antibodies
Blastomyces Antibody
Coccidioides Antibody
Histoplasma Mycelia
Histoplasma Yeast
Semi-Quantitative Complement Fixation/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunodiffusion. Not recommended. Refer to individual fungal antibody tests, as relevant to patient exposure(s).
3000235 Fungal Antibodies with Reflex to Blastomyces dermatitidis Antibodies by Immunodiffusion Fungal Panel Serum Aspergillus Antibodies
Blastomyces Antibody
Coccidioides Antibody
Histoplasma Mycelia
Histoplasma Yeast
Semi-Quantitative Complement Fixation/Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunodiffusion. Not recommended. Refer to individual fungal antibody tests, as relevant to patient exposure(s).
0050100 Aspergillus Antibody by Compliment Fixation (CF) Aspergillus Serum Negative fungal serology does not rule out the possibility of current infection. Semi-Quantitative Complement Fixation Not recommended for the diagnosis of invasive aspergillosis. Consider ordering Aspergillus Galactomannan Antigen by EIA, Serum (0060068) or Aspergillus Galactomannan Antigen by EIA, Bronchoscopy (2003150).
0050171 Aspergillus spp. Antibodies by Immunodiffusion Aspergillus Serum Filtrates of Aspergillus fumigatus, Aspergillus flavus, Aspergillus niger, and Aspergillus terreus. Qualitative Immunodiffusion In general, immunodiffusion measures IgG and a positive result may suggest past infection. The test is positive in about 90% of sera from patients with aspergilloma and 50-70% of patients with allergic bronchopulmonary aspergillosis. A negative test (none detected) does not exclude aspergillosis.
0050101 Aspergillus Antibodies by CF and ID Aspergillus Serum Aspergillus Antibody by CF
Aspergillus spp. Antibodies by Immunodiffusion
Not recommended for the diagnosis of invasive aspergillosis. Consider ordering Aspergillus Galactomannan Antigen by EIA, Serum (0060068) or Aspergillus Galactomannan Antigen by EIA, Bronchoscopy (2003150).
0097771 Aspergillus fumigatus Antibody, IgG by ELISA Aspergillus Serum Aspergillus fumigatus Antibody, IgG Aspergillus fumigatus-specific IgG is one component of testing recommended to establish the diagnosis of allergic bronchopulmonary aspergillosis (ABPA); it is not appropriate for diagnosing invasive aspergillosis.
2004243 Allergic Bronchopulmonary Aspergillosis (ABPA) Panel Aspergillus Serum Immunoglobulin E
Allergen, Fungi/Mold, A. fumigatus IgE
A. fumigatus #1 Ab, Precipitin
A. fumigatus #6 Ab, Precipitin
Quantitative ImmunoCAP Fluorescent Enzyme Immunoassay/Qualitative Immunodiffusion
3000236 Blastomyces dermatitidis Antibodies by EIA with Reflex to Immunodiffusion, Serum Blastomyces Serum If Blastomyces antibodies are equivocal or positive by EIA then Blastomyces Immunodiffusion will be added Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunodiffusion
3000231 Blastomyces dermatitidis Antibodies by EIA with Reflex to Immunodiffusion, CSF Blastomyces CSF If Blastomyces antibodies are equivocal or positive by EIA then Blastomyces Immunodiffusion will be added Semi-Quantitative Enzyme-Linked Immunosorbent Assay/Qualitative Immunodiffusion
0050172 Blastomyces dermatitidis Antibodies by Immunodiffusion Blastomyces Serum Blastomyces dermatitidis Abs, Precipitin Qualitative Immunodiffusion .
Not recommended as a stand-alone test. Refer to Blastomyces dermatitidis Antibodies by EIA with Reflex to Immunodiffusion, Serum (3000236).
0050588 Coccidioides Antibodies Panel, Serum by CF, ID, ELISA Coccidioides Serum Coccidioides Antibody by CF
Coccidioides immitis Antibodies by Immunodiffusion
Coccidioides Antibody, IgM and IgG by ELISA
Preferred serology test to detect coccidioidomycosis (Valley fever).
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
0050178 Coccidioides Antibody, IgM by ELISA Coccidioides Serum Coccidioides Antibody, IgM by ELISA Not recommended as a stand-alone test. For diagnosis of coccidioidomycosis (Valley fever), refer to Coccidioides Antibodies Panel, Serum by CF, ID, ELISA (0050588) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
0050179 Coccidioides Antibody, IgG by ELISA Coccidioides Serum Coccidioides Antibody, IgG by ELISA Not recommended as a stand-alone test. For diagnosis of coccidioidomycosis (Valley fever), refer to Coccidioides Antibodies Panel, Serum by CF, ID, ELISA (0050588) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays
0050137 Coccidioides Antibodies, IgG and IgM by ELISA Coccidioides Serum Coccidioides Antibody, IgM and IgG by ELISA Aid in diagnosis of coccidioidomycosis (Valley fever). Preferred test is Coccidioides Antibodies Panel, Serum by CF, ID, ELISA (0050588) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
0050170 Coccidioides Antibody by CF Coccidioides Serum CF measures both IgM and IgG. As single antibody titers are generally not diagnostic, paired specimens are preferred Titers may aid in monitoring coccidioidomycosis (Valley fever) and treatment response. For initial establishment of diagnosis, refer to Coccidioides Antibodies Panel, Serum by CF, ID, ELISA (0050588) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
0050183 Coccidioides immitis Antibodies by Immunodiffusion Coccidioides Serum This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens. Not recommended. For diagnosis of coccidioidomycosis (Valley fever), refer to Coccidioides Antibodies Panel, Serum by CF, ID, ELISA (0050588) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
3000061 Coccidioides Antibodies Panel, CSF by CF, ID, ELISA Coccidioides CSF Coccidioides immitis by Immunodiffusion, CSF
Coccidioides Antibody by CF, CSF
Coccidioides Antibody IgG ELISA, CSF
Coccidioides Antibody IgM ELISA, CSF
Semi-Quantitative Complement Fixation/Qualitative Immunodiffusion/Semi-Quantitative Enzyme-Linked Immunosorbent Assay
For Coccidioides, immunodiffusion (ID) measures IgM antibody, while complement fixation (CF) measures both IgG and IgM. ELISA tests can be used to detect both coccidioidal IgG and IgM antibodies. While elevated single antibody titers may be diagnostic, paired specimens are preferred. Acute and convalescent specimens (drawn at least 21 days apart), showing a fourfold or greater rise in titer, are diagnostic.
3000056 Coccidioides Antibody IgM ELISA, CSF Coccidioides CSF Coccidioides Antibody, IgM by ELISA Not recommended as a stand-alone test. For diagnosis of coccidioidal meningitis (Valley fever), refer to Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
3000055 Coccidioides Antibody IgG ELISA, CSF Coccidioides CSF Coccidioides Antibody, IgG by ELISA Not recommended as a stand-alone test. For diagnosis of coccidioidal meningitis (Valley fever), refer to Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
3000057 Coccidioides Antibodies, IgG and IgM by ELISA, CSF Coccidioides CSF Coccidioides Antibody, IgM and IgG by ELISA Aid in diagnosis of coccidioidal meningitis (Valley fever). Preferred test is Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
3000058 Coccidioides immitis by Immunodiffusion, CSF Coccidioides CSF This test uses culture filtrates of Coccidioides immitis and includes IDCF and IDTP antigens. Not recommended. For diagnosis of coccidioidal meningitis (Valley fever), refer to Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays
3000059 Coccidioides Antibody by CF, CSF Coccidioides CSF CF measures both IgM and IgG. As single antibody titers are generally not diagnostic, paired specimens are preferred. Titers may aid in monitoring coccidioidal meningitis (Valley fever) and treatment response. For initial establishment of diagnosis, refer to Coccidioides Antibodies Panel, CSF by CF, ID, ELISA (3000061) which combines complement fixation, immunodiffusion, and enzyme-linked immunosorbent assays.
0050625 Histoplasma Antibodies by CF Histoplasma Serum Histoplasma Yeast, CF
Histoplasma Mycelia, C
Not recommended as a stand-alone test. Refer to Histoplasma Antibodies by CF & ID (0050627).
0050174 Histoplasma spp. Antibodies by Immunodiffusion Histoplasma Serum The immunodiffusion test can detect precipitins to specific Histoplasma protein antigens (M and H).F Qualitative Immunodiffusion
Not recommended as a stand-alone test. Refer to Histoplasma Antibodies by CF & ID (0050627).
0050627 Histoplasma Antibodies by CF & ID Histoplasma Serum Histoplasma spp. Antibodies by Immunodiffusion
Histoplasma Yeast, CF
Histoplasma Mycelia, CF
Aid in the diagnosis of histoplasmosis. Recommend testing in conjunction with Histoplasma Antigen by EIA, Serum (0092522) and Histoplasma Galactomannan Antigen Quantitative by EIA, Urine (2009418).