ARUP offers nucleic acid amplification (NAA) testing for the diagnosis of current COVID-19 infection and two immunoglobulin G (IgG) antibody tests (targeting spike and nucleocapsid proteins, respectively) to evaluate individuals for exposure to SARS-CoV-2.

 

Diagnostic Tests

SARS-CoV-2 (COVID-19) by NAA (3002638)

Clinical Use:

Recommended molecular testing (NAA) for the detection of SARS-CoV-2 for symptomatic patients. Because symptoms for COVID-19 are similar to those of other respiratory infections, a clinical diagnosis alone is not sufficient to make a COVID-19 diagnosis.

Benefits:

  • We offer a rapid turnaround time.
  • ARUP’s molecular assays are designed to detect several SARS-CoV-2 RNA gene targets, allowing for the detection of COVID-19 variants.
  • We accept multiple specimen types, including nasopharyngeal swab, oropharyngeal swab, nasal swab, or saliva specimens.

Antibody Tests

COVID-19 IgG, Qualitative by CIA (3002776)

Clinical Use:

Use for the qualitative detection of IgG antibodies against the nucleocapsid protein of SARS-CoV-2 that develop in response to natural infection with SARS-CoV-2 (COVID-19 infection). These antibodies do not develop as a result of a COVID-19 vaccination.

COVID-19 IgG (Spike), Semi-Quantitative by CIA (3003648)

Clinical Use:

Use for the detection of IgG antibodies against the spike protein (S1) of SARS-CoV-2 that develop in response to natural infection with SARS-CoV-2 or from a COVID-19 vaccination.

Benefits:

  • We offer a rapid turnaround time.
  • Our highly sensitive and specific assays detect low levels of IgG antibodies.

Related Testing

Vaccine-Induced Immune Thrombotic Thrombocytopenia

Unusual thrombotic events with thrombocytopenia have been reported in a small number of patients following receipt of two SARS-CoV-2 vaccines (AstraZeneca and Johnson and Johnson/Janssen). For more information, please refer to the Quick Answers for Clinicians section of the Heparin Induced Thrombocytopenia - HIT ARUP Consult topic.

Clinical Resources

Testing Guidance

ARUP’s COVID-19 assays are offered under FDA Emergency Use Authorization (EUA). Please visit the FDA web page, EUA Authorized Serology Test Performance, for more information.

Decision Support: ARUP Consult®

ARUP provides ARUP Consult as a resource to hospital and laboratory clients, healthcare providers, and patients at no cost.