The Institute for Clinical and Experimental Research® is focused on the development of new diagnostic assays in a wide range of disciplines. Researchers at the institute regularly publish in respected, peer-reviewed journals, give presentations at national and international organizations, author books and book chapters, and develop new tests.

Publications by Year

2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019

Recent Publications

Profaizer T, Lazár-Molnár E.Cell-Free DNA and its Applications in Laboratory Medicine. ASHI Quarterly 2020;44(2):22-26.

​Lawrence R, Prill H, Vachali P, Adintor EG, Wan RY, Burto BK, Pasquali M, Crawford BE. Characterization of disease-specific chondroitin sulfate non-reducing end accumulation in mucopolysaccharidosis IVA. Glycobiology 2020;30(7):433-445.            

​Profaizer T, Pole A, Monds C, Delgado J, Lázár-Molnár E.Clinical utility of next generation sequencing based HLA typing for disease association and pharmacogenetic testing.Human Immunology 2020;81(7):354-360.

​McDonald J, Bayrak-Toydemir P, DeMille D, Wooderchak-Donahue W, Whitehead K.Curaçao Diagnostic Criteria for Hereditary Hemorrhagic Telangiectasia Is Highly Predictive of a Pathogenic Variant in ENG or ACVRL1 (HHT1 and HHT2).Genetics in Medicine 2020;22(7):1201-1205.   

​Deftereos G, Schmechel SC, Waner EE, Itani M, Dighe MK, Tylee TS.Differential Outcomes of Patients With Thyroid FNA Diagnoses of AUS/FLUS With and Without Nuclear Atypia: The Potential Need for Separation in the Bethesda System.​Diagnostic Cytopathology2020;48(7):610-617.        

​Calvaresi EC, Genzen JR.Evaluating Percentage-Based Reporting of Glucose-6-Phosphate Dehydrogenase (G6PD) Enzymatic Activity. American Journal of Clinical Pathology 2020;154(2):248-254.

​Ballout ​RA, Dickerson C, Wick MJ, Al-Sweel N, Openshaw AS, Srivastava S, Swanson L, Bramswig NC, Kuechler A, Hong B, Fleming LR, Curry KT, Robertson SP, Andersen EF, El-Hattab AW​. Int22h1/Int22h2-mediated Xq28 Duplication Syndrome: De Novo Duplications, Prenatal Diagnoses, and Additional Phenotypic Features. Human Mutation 2020;41(7):1238-1249.    

​Pratt VM, Cavallari LH, Del Tredici AL, Hachad H, Ji Y, Kalman LV, Ly RC, Moyer AM, Scott SA, Whirl- Carrillo M, Weck KE.Recommendations for Clinical Warfarin Sensitivity Genotyping Allele Selection: A Report of the Association for Molecular Pathology and College of American Pathologists. Journal of Molecular Diagnostics 2020; 22(7):847-859.

​Riggs ER, Andersen EF, Kantarci S, Kearney H, Patel A, Raca G, Ritter DI, South ST, Thorland EC, Pineda-Alvarez D, Aradhya S, Martin CL; American College of Medical Genetics and Genomics.Response to Maya Et Al. Genetics in Medicine 2020;22(7):1278-1279.

Agarwal AM, Rets A.Laboratory Approach to Investigation of Anemia With a Focus on Pyruvate Kinase Deficiency.International Journal of Laboratory Hematology 2020;42 Suppl 1:107-112.

Hayward CPM, George TI, Van Cott EM, Smock KJ.Patient Advocacy and Its Importance to Laboratory Medicine Practice.International Journal of Laboratory Hematology 2020;42 Suppl 1:21-22.

Kroner GM, Johnson-Davis KL, Doyle K, McMillin GA.Cannabinol (CBN) Cross-Reacts With Two Urine Immunoassays Designed to Detect Tetrahydrocannabinol (THC) Metabolite.Journal of Applied Laboratory Medicine 2020;5(3):569-574.

Mathison BA, Kohan JL, Walker JF, Smith RB, Ardon O, Couturier MR.Detection of Intestinal Protozoa in Trichrome-stained Stool Specimens by use of Deep Convolutional Neural Network.Journal of Clinical Microbiology 2020;58(6):e02053-19.

Wesolowski LG, Chavez PR, Cárdenas AM, Katayev A, Slev P, Valsamakis A, Wang YF, Yao JD, Dougherty C, Gillim-Ross L, Harmon C, Delaney KP.Routine HIV Test Results in 6 US Clinical Laboratories Using the Recommended Laboratory HIV Testing Algorithm With Geenius HIV 1/2 Supplemental Assay.Sexually Transmitted Diseases 2020;47(5S Suppl 1):S13-S17.

Smith KP, Wang H, Durant T, Mathison BA, Sharp S, Kirby J, Long SW, Rhoads DD.Applications of Artificial Intelligence in Clinical Microbiology Diagnostic Testing.Clinical Microbiology Newsletter 2020;42(8):61-70.

Stewart RL, Matynia AP, Factor RE, Varley KE.Spatially-resolved Quantification of Proteins in Triple Negative Breast Cancers Reveals Differences in the Immune Microenvironment Associated With Prognosis.Scientific Reports 2020;10(1):6598.

Schmidt R, Layfield LJ.Authors Response: The Milan System for Reporting Salivary Gland Cytopathology: A Study of Inter-Observer Reproducibility.Diagnostic Cytopathology 2020;48(3):287.

Wojewoda CM, Anderson NW, Humphries RM, Martin IW, Mathison BA, McMullen AR, Nolte FS, Peaper DR, Pillai DR, Rauch CA, Rhoads DD, Sharp SE, She RC, Simner PJ, Sullivan KV, Theel ES, Theiss AM, Thomson RB Jr, Pritt BS.College of American Pathologists (CAP) Microbiology Committee Perspective: The Need for Verification Studies. Journal of Clinical Microbiology 2020; 58(4). pii: e02105-19.

Erickson JA, Case K, Neider C, Johnson LM.Stool reducing sugars and stool pH are poor screening tests for intestinal disaccharidase deficiencies in children.The Journal of Applied Laboratory Medicine 2020;5(2):257-262.

Riggs ER, Andersen EF, Cherry AM, Kantarci S, Kearney H, Patel A, Raca G, Ritter DI, South ST, Thorland EC, Pineda-Alvarez D, Aradhya S, Martin CL, ACMG.Technical standards for the interpretation and reporting of constitutional copy-number variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics (ACMG) and the Clinical Genome Resource (ClinGen).Genetics in Medicine 2020;22 (2), 245-257.

He L, Rockwood AL, Agarwal AM, Anderson LC, Weisbrod CR, Hendrickson CL, Marshall AG.Top-down Proteomics-A Near-Future Technique for Clinical Diagnosis?Annals of Translational Medicine 2020;8(4),136.

Radhakrishnan SV, Luetkens T, Scherer SD,Davis P, Vander Mause ER, Olson ML, Yousef S, Panse J, Abdiche Y, Li KD,Miles RR,Matsui W, Welm AL, Atanackovic D.CD229 CAR T Cells Eliminate Multiple Myeloma and Tumor Propagating Cells Without Fratricide.Nature Communications 2020;11(1):798.

Hong SL, Dellicour S, Vrancken B, Suchard MA,Pyne MT, Hillyard DR, Lemey P, Baele G.In search for covariates of HIV-1 subtype B spread in the United States - A cautionary tale of Large-scale Bayesian phylogeogrphy.Viruses 2020;12(2).

Nix DA,Hellwig S, Conley C, Alun T, Fuertes C, Hamil C, Bhetariya P, Garrido-Laguno I, Marth G,Bronner MP,Underhill HR.The stochastic nature of errors in next-generation sequencing of circulating cell-free DNA.PLoS One 2020;15(2):e0229063.

Hoshitsuki K, Crews KR, Yang W, Smith CA, Hankins JS, Turner AJ, Broeckel U, McMillin GA, Relling MV, Haidar CE. Challenges in clinical implementation of CYP2D6 genotyping: choice of variants to test affects phenotype determination. Genetics in Medicine 2020;22(1):232-233.

Anderson DR, Viau K, Botto LD, Pasquali M, Longo N. Clinical and biochemical outcomes of patients with medium-chain acyl-CoA dehydrogenase deficiency. Molecular Genetics and Metabolism 2020; 129(1):13-19.

Schumacher JA, Holgard V, Sial F, Pearson L, Patel JL, Karner KH. Detection and Quantification of FLT3 Internal Tandem Duplication Mutations Do Not Vary Significantly Between Whole Blood and Blast-Enriched Samples​. American Journal of Clinical Pathology 2020;153(2):251-257.

​Lu J, Grenache DJ. Development of an Automated Enzymatic Method to Quantify Pyruvate Kinase in Red Blood Cells. The Journal of Applied Laboratory Medicine 2020;5(1):54-61.

​Kushnir MM, Peterson LK, Strathmann FG. Parathyroid Hormone Related Protein (PTHrP) in Cerebrospinal Fluid in Health and Disease. Clinical Laboratory International 2020;16-18.