Gwendolyn A. McMillin, PhD, DABCC (CC,TC), FADLM

Professor (Clinical), University of Utah School of Medicine

Education

• Doctorate Degree—Pharmacology, University of Utah
• Fellowship—Clinical Chemistry, University of Utah

Certification/Affiliations

• American Board of Clinical Chemistry (Clinical Chemistry, Toxicological Chemistry)

Research Interests

• Pharmacogenomics
• Newborn drug exposures
• Analytical methods

Awards

• Past Chair Award, TDM and Toxicology Division, American Association for Clinical Chemistry (now ADLM), 2014
• Ellis Benson Young Investigator Award, Academy of Clinical Laboratory Physicians and Scientists, 2012
• Outstanding Speaker Award, American Association for Clinical Chemistry (now ADLM), 2009, 2011, and 2013

Recent Publications

• McMillin GA, Morad AW, Boyd JM, et al. Biological testing and interpretation of laboratory results associated with detecting newborns with substance exposure. Clin Chem. 2024;70(7):934-947.
• Mc Laughlin AM, Helland T, Klima F, et al. Nonlinear mixed-effects model of Z-endoxifen concentrations in tamoxifen-treated patients from the CEPAM cohort. Clin Pharmacol Ther. 2024;116(3):690-702.
• Baryeh K, Zhou R, Brown E, et al. Retrospective data analysis reveals unusual metabolism pattern of ethanol in pediatrics as compared to adult and geriatric populations. J Appl Lab Med. 2024;9(4):767-775.
• Boyd JM, Kelly BN, McMillin GA. Prevalence of gabapentinoid and opioid copositives in a reference laboratory patient population. J Appl Lab Med. 2024;9(4):861-863.
• Watson CJ, McMillin GA, Burns MM. False-negative confirmatory testing in patients with cannabinoid-positive urine drug screens. JAMA Pediatr. 2024;178(2):199-201.
• Hughs ML, McMillin GA. 11-nor-9-carboxy-Δ8-tetrahydrocannabinol, 7-carboxy cannabidiol, and 11-nor-9-carboxy-Δ9-tetrahydrocannabinol in urine by LC-MS/MS. Methods Mol Biol. 2024;2737:161-174.
• Merrigan SD, Yang YK, McMillin GA, et al. Detection of 41 drugs and metabolites in urine with internal hydrolysis control by liquid chromatography-tandem mass spectrometry. Methods Mol Biol. 2024;2737:229-247.
• Metz TD, Allshouse AA, McMillin GA, et al. Cannabis exposure and adverse pregnancy outcomes related to placental function. JAMA. 2023;330(22):2191-2199.
• Snozek CLH, McMillin GA, Nwosu A, et al. Nicotine and tobacco alkaloid testing and challenges: lessons learned from a College of American Pathologists proficiency testing survey. Arch Pathol Lab Med. 2023;147(6):634-642.
• Bithi N, Merrigan SD, McMillin GA. Does labetalol trigger false positive drug testing results? J Addict Med. 2023;17(3):e209-e210.
• Pandya V, McMillin GA, Young BA. Deceptively simple: Can urine samples from CLIA-waived urine drug screen devices be reused for confirmatory testing? J Appl Lab Med. 2023;8(2):341-346.
• Pandya V, Wilker C, McMillin GA. Can umbilical cord and meconium results be directly compared? Analytical approach matters. J Anal Toxicol. 2023;47(1):96-105.
• Hughs M, Kish-Trier E, OBrien A, et al. Analysis of mitragynine and speciociliatine in umbilical cord by LC-MS-MS for detecting prenatal exposure to kratom. J Anal Toxicol. 2023;46(9):957-964.
• Marzinke MA, Clarke W, Dietzen DJ, et al. The VALIDity of laboratory developed tests: leave it to the experts? J Mass Spectrom Adv Clin Lab. 2022;27:1-6.
• Smid MC, Allshouse AA, McMillin GA, et al. Umbilical cord collection and drug testing to estimate prenatal substance exposure in Utah. Obstet Gynecol. 2022;140(2):153-162.
• Bajaj AO, Kushnir MM, Kish-Trier E, et al. LC-MS/MS method for measurement of thiopurine nucleotides (TN) in erythrocytes and association of TN concentrations with TPMT enzyme activity. Front Pharmacol. 2022;13:836812.
• Hunsaker JJH, La'ulu SL, LaGrave D, et al. Tobacco and cannabis use during pregnancy. Am J Clin Pathol. 2022;157(1):146-152.
• Nelson HA, Wood KE, McMillin GA, et al. Umbilical cord drug screening in multiple births: experience from a reference laboratory and academic medical center. J Anal Toxicol. 2022;46:611-618.
• Metz TD, McMillin GA, Silver RM, et al. Quantification of prenatal marijuana use: evaluation of the correlation between self-report, serum, urine and umbilical cord assays among women delivering at two urban Colorado hospitals. Addiction. 2022;117(1):172-181.
• Langman LJ, Gaskins J, Korte E, et al. Endogenous and iatrogenic sources of variability in response to opioid therapy in post-surgical and injured orthopedic patients. Clin Chim Acta. 2021;522:105-113.
• Khushman M, Patel GK, Maharjan AS, et al. The prevalence and clinical relevance of 2R/2R TYMS genotype in patients with gastrointestinal malignancies treated with fluoropyrimidine-based chemotherapy regimens. Pharmacogenomics J. 2021;21(3):308-317.
• Okoye NC, McMillin GA. Patterns of neonatal co-exposure to gabapentin and commonly abused drugs observed in umbilical cord tissue. J Anal Toxicol. 2021;45(5):506-512.
• Bernard PS, Wooderchak-Donahue W, Wei M, et al. Potential utility of pre-emptive germline pharmacogenetics in breast cancer. Cancers (Basel). 2021;13(6):1219.