Archana Mishra Agarwal, MD

Professor (Clinical), University of Utah School of Medicine

Specialties

• Hematopathology
• RBC membrane and enzyme disorders
• Hemoglobinopathies/thalassemia
• Molecular hematology

Education

• Medical Degree—Assam Medical College, India
• Residency—Anatomic and Clinical Pathology, University of Utah School of Medicine
• Fellowship—Hematopathology, University of Utah School of Medicine
• Fellowship—Molecular Genetic Pathology, University of Utah School of Medicine

Certification/Affiliations

• American Board of Pathology (Anatomic Pathology and Clinical Pathology, Hematology, Molecular Genetic Pathology)

Research Interests

• Red cell enzymopathies
• Hemoglobinopathies
• Molecular hematopathology

Recent Publications

• Gorfinkel L, Wachter F, Luo HY, et al. Transient neonatal hemolytic anemia due to the novel gamma globin gene mutation HBG2:C.290T>C, p.Leu97Pro (hemoglobin Wareham). Pediatr Blood Cancer. 2023;70(1):e30067.
• Lin Y, Agarwal AM, Marshall AG, et al. Characterization of structural hemoglobin variants by top-down mass spectrometry and R programming tools for rapid identification. J Am Soc Mass Spectrom. 2022;33(1):123-130.
• Montgomery HD, Agarwal AM, Lim MY. A case of azathioprine-induced aplastic anemia. Int J Lab Hematol. 2022;44(6):1015-1016.
• Agarwal AM, Rets A. Laboratory approach to investigation of anemia in pregnancy. Int J Lab Hematol. 2021;43 Suppl 1:65-70.
• Lozano-Chinga M, Draper L, George TI, et al. Bone marrow necrosis in pediatric malignancies: 10-year retrospective review and review of literature. Pediatr Blood Cancer. 2021;68(3):e28806.
• Cowman SJ, Fuja DG, Liu XD, et al. Correction: Macrophage HIF-1α is an independent prognostic indicator in kidney cancer. Clin Cancer Res. 2021 Jun 1;27(11):3265.
• Pond GR, Agarwal A, Ornstein M, et al. Clinical outcomes of platinum-ineligible patients with advanced urothelial carcinoma treated with first-line PD1/L1 inhibitors. Clin Genitourin Cancer. 2021;19(5):425-433.
• Bahr TM, Agarwal AM, Meznarich JA, et al. Thirty-five males with severe (class 1) G6PD deficiency (c.637G>T) in a North American family of European ancestry. Blood Cells Mol Dis. 2021;92:102625.
• Bahr TM, Agarwal AM, Christensen RD. Does heterozygosity for UGT1A1 *28 convey increased risk for severe neonatal jaundice? J Perinatol. 2021;41(4):658-660.
• Iglesias Cardenas F, Agarwal AM, Vagher J, et al. Two clonally distinct B-cell lymphomas reveal the diagnosis of XLP1 in a male child and his asymptomatic male relatives: case report and review of the literature. J Pediatr Hematol Oncol. 2021;43(8):e1210-e1213.
• Maglic D, Moss W, Pires G, et al. A case report of misdiagnosed breast implant-associated anaplastic large cell lymphoma with lymphatic extension. Plast Reconstr Surg Glob Open. 2021;9(11):e3916.
• Kim SJ, Song J, Reading NS, et al. Novel mechanism of hereditary pyropoikilocytosis phenotype due to co-inheritance of β globin and α spectrin mutations. Am J Hematol. 2021;96(5):E150-E154.
• Bahr TM, Knudsen MC, Lozano-Chinga M, et al. Infantile pyknocytosis: end-tidal CO, %micro-R measurements, next-generation sequencing, and transfusion avoidance with darbepoetin. Biomed Hub. 2020;5(3):227-234.
• Meznarich JA, Rets A, Agarwal AM, et al. Novel, de novo, beta-globin variant with decreased oxygen affinity (HBB:c.317T>A, "hemoglobin St. George") in a healthy child with low oxygen saturations and anemia. Am J Hematol. 2021;96(12):E448-E450.
• Bahr TM, Lozano-Chinga M, Agarwal AM, et al. A novel variant in G6PD (c.1375C>G) identified from a Hispanic neonate with extreme hyperbilirubinemia and low G6PD enzymatic activity. Neonatology. 2020;117(4):532-535.
• Bahr TM, Lozano-Chinga M, Agarwal AM, et al. Dizygotic twins with prolonged jaundice and microcytic, hypochromic, hemolytic anemia with pyropoikilocytosis. Blood Cells Mol Dis. 2020;85:102462.
• Samha L, Sirdah MM, Reading NS, et al. Molecular understanding of severe cases of β-thalassemia in the Nablus region, West Bank, Palestine. Hemoglobin. 2020;44(2):128-130.
• Rets AV, Reading NS, Agarwal AM. δ-globin chain variants associated with decreased Hb A2 levels: a national reference laboratory experience. Hemoglobin. 2020;44(6):438-441.
• Agarwal AM, Rets A, et al. Laboratory approach to investigation of anemia with a focus on pyruvate kinase deficiency. Int J Lab Hematol. 2020;42 Suppl 1:107-112.
• He L, Rockwood AL, Agarwal AM, et al. Top-down proteomics—a near-future technique for clinical diagnosis? Ann Transl Med. 2020;8(4):136.
• Cowman SJ, Fuja DG, Liu XD, et al. Macrophage HIF-1α is an independent prognostic indicator in kidney cancer. Clin Cancer Res. 2020;26(18):4970-4982.
• Stenehjem DD, Hahn AW, Gill DM, et al. Predictive genomic markers of response to VEGF targeted therapy in metastatic renal cell carcinoma. PLoS One. 2019;14(1):e0210415.
• Patel AB, Franzini A, Leroy E, et al. JAK2 ex13InDel drives oncogenic transformation and is associated with chronic eosinophilic leukemia and polycythemia vera. Blood. 2019;134(26):2388-2398.
• Agarwal A, Sonpavde G. A new subtyping model for residual invasive disease after cisplatin-based neoadjuvant chemotherapy for muscle invasive bladder cancer. Transl Androl Urol. 2019;8(Suppl 3):S254-S256.
• He L, Rockwood AL, Agarwal AM, et al. Diagnosis of hemoglobinopathy and β-thalassemia by 21 tesla fourier transform ion cyclotron resonance MS and MS/MS of hemoglobin from blood. Clin Chem. 2019;65(8):986-994. Epub.
• Rets A, Clayton AL, Christensen RD, et al. Molecular diagnostic update in hereditary hemolytic anemia and neonatal hyperbilirubinemia. Int J Lab Hematol. 2019.; 41(Suppl 1):95-101.
• Bahr TM, Christensen RD, Agarwal AM, et al. The Neonatal Acute Bilirubin Encephalopathy Registry (NABER):  background, aims, and protocol. Neonatology. 2019;115(3):242-246.
• Archana M Agarwal. Ankyrin mutations in hereditary spherocytosis. Commentary. Acta Haematologica. 2019;141(2):63-64.
• Polega J, Stumph J, Agarwal A, et al. Novel mutation in SPTA 1 gene associated with severe hemolytic anemia. J Pediatr Neonatal Care. 2018;8(5):250-253.