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Julia A. Bridge, MD, FACMG Medical Director: Solid Tumor FISH, ARUP Laboratories
Professor (Clinical), University of Utah School of Medicine Specialties Bone and soft tissue pathology Cytopathology Cytogenetics and molecular oncology (solid tumors) Education Medical Degree—University of Nebraska Medical Center Residency—Pathology, University of Kansas Medical Center Fellowship—Molecular Genetics, Southwest Biomedical Research Institute Fellowship—Cytogenetics, University of Kansas Medical Center Fellowship—Cytogenetics, University of Nebraska Medical Center Certification/Affiliations American Board of Medical Genetics (Clinical Cytogenetics) American Board of Pathology (Anatomic Pathology) Research Interests Bone and soft tissue tumors Molecular and cytogenomic profiling of solid tumors Awards Maude Abbott Lecture Award, United States and Canadian Academy of Pathology (USCAP) President, United States and Canadian Academy of Pathology (USCAP) Amelia F. and Austin L. Vickery Jr., Chair in Pathology, University of Nebraska Foundation K. Mostofi Distinguished Service Award, USCAP CTOS Herman Suit Special Award Lecture, Connective Tissue Oncology Society President, International Society of Bone and Soft Tissue Pathology Secretarial Appointee, Department of Veterans Affairs, Genomic Medicine Program Advisory Committee Fred Waldorf Stewart Award, Memorial Sloan Kettering Cancer Center Young Investigator Award, USCAP Kappa Delta Young Investigator Award, American Academy of Orthopaedic Surgeons Kappa Delta Ann Doner Vaughn Award, American Academy of Orthopaedic Surgeons Recent Publications O'Connor P, Bridge JA, Meis JM, et al. Myxoid "pauci-hemosiderotic" fibrolipomatous tumour: a diagnostic challenge . Histopathology . 2025;86(4):647-649. Papke DJ Jr, Chrisinger JSA, French CA, et al. MAD::NUT-fusion sarcoma: a sarcoma class with NUTM1, NUTM2A and NUTM2G fusions and possibly distinctive subtypes . Mod Pathol . 2025:100729 Acosta AM, Fletcher CDM, Sholl LM, et al. Fluorescence in-situ hybridization assessment of spindle cell-rich testicular sex cord stromal tumors demonstrates multiple chromosomal gains across histologic subtypes . Hum Pathol . 2024;153:105652 Sta Ines FMG, Marketkar S, Ng S, et al. Myoid hamartoma of the breast with HMGA2 rearrangement and associated in-situ and invasive carcinoma: case report and review of literature . Int J Surg Pathol . 2024:10668969241271420. Collins K, Bridge JA, Mehra R, et al. Renal epithelioid angiomyolipomas overexpress TFE3 and the TFE3-regulated gene TRIM63 in the absence of TFE3 rearrangement . Virchows Arch . 2024;485(3):471-478 Amin SE, Lewis JS Jr, Bridge JA, et al. DEK::AFF2 fusion-associated squamous cell carcinoma: a case series with literature review on an emerging and challenging entity . Head Neck Pathol . 2024;18(1):86. Whaley RD, Agaimy A, Bridge JA, et al. Xanthogranulomatous epithelial tumors/keratin-positive giant cell-rich tumors involving the head and neck: report of seven cases and review of the literature . Virchows Arch . 2024;485(4):605-613. Machado I, Agaimy A, Giner F, et al. The value of GLI1 and p16 immunohistochemistry in the premolecular screening for GLI1-altered mesenchymal neoplasms . Virchows Arch . 2024;484(5):765-775. Bridge JA, Halling KC, Moncur JT, et al. RNA sequencing for solid tumor fusion gene detection: proficiency testing practice and performance comparison . Arch Pathol Lab Med . 2024;148(5):538-544. Surucu A, de Biase D, Ricci C, et al. Beta-catenin alterations in post-chemotherapy yolk sac tumor, postpubertal-type with enteroblastic features . Mod Pathol . 2024;37(7):100513. Mezzacappa FM, Smith FK, Zhang W, et al. Potential prognostic determinants for FET::CREB fusion-positive intracranial mesenchymal tumor . Acta Neuropathol Commun . 2024;12(1):17. Machado I, Llombart-Bosch A, Charville GW, et al. Sarcomas with EWSR1::non-ETS fusion (EWSR1::NFATC2 and EWSR1::PATZ1) . Surg Pathol Clin . 2024;17(1):31-55. Hagemann IS, Bridge JA, Tafe LJ, et al. Current laboratory testing practices for assessment of ERBB2/HER2 in endometrial serous carcinoma and colorectal carcinoma . Arch Pathol Lab Med . 2023;147(10):1148-1157. Crowley HM, Georgantzoglou N, Tse JY, et al. Expanding our knowledge of molecular pathogenesis in histiocytoses: solitary soft tissue histiocytomas in children with a novel CLTC::SYK fusion . Am J Surg Pathol . 2023;47(10):1108-1115. Gangahar CN, Dehner CA, Wang DP, et al. Intraosseous hibernoma: clinicopathologic and imaging analysis of 18 cases . Histopathology . 2023;83(1):40-48. Machado I, Hosler GA, Traves V, et al. Superficial GLI1-amplified mesenchymal neoplasms: expanding the spectrum of an emerging entity which reaches the realm of dermatopathology . J Cutan Pathol . 2023;50(6):487-499. Zota V, Siegal GP, Kelly D, et al. Validation of PRKCB immunohistochemistry as a biomarker for the diagnosis of Ewing sarcoma . Fetal Pediatr Pathol . 2023;42(2):241-252. Acosta AM, Bridge JA, Dal Cin PS, et al. Inflammatory and nested testicular sex cord tumor: a novel neoplasm with aggressive clinical behavior and frequent EWSR1::ATF1 gene fusions . Am J Surg Pathol . 2023;47(4):504-517. Bove JVMG, Webster F, Amary F, et al. Datasets for the reporting of primary tumour in bone: recommendations from the International Collaboration on Cancer Reporting (ICCR) . Histopathology . 2023;82(4):531-540. Palsgrove DN, Rooper LM, Stevens TM, et al. GLI1-altered soft tissue tumors of the head and neck: frequent oropharyngeal involvement, p16 immunoreactivity, and detectable alterations by DDIT3 break apart FISH . Head Neck Pathol . 2022;16(4):1146-1156. Georgantzoglou N, Green D, Winnick KN, et al. Molecular investigation of ALK-rearranged epithelioid fibrous histiocytomas identifies CLTC as a novel fusion partner and evidence of fusion-independent transcription activation . Genes Chromosomes Cancer . 2022;61(8):471-480. Brat DJ, Aldape K, Bridge JA, et al. Molecular biomarker testing for the diagnosis of diffuse gliomas . Arch Pathol Lab Med . 2022;146(5):547-574. Ramkissoon SH, Fernandes H, Lopez-Terrada DH, et al. Clinical laboratory testing practices in diffuse gliomas prior to publication of 2021 World Health Organization Classification of Central Nervous System Tumors . Arch Pathol Lab Med . 2022;147(5):518-524. Strait AM, Bridge JA, Iafrate AJ, et al. Mammary-type myofibroblastoma with leiomyomatous differentiation: a rare variant with potential pitfalls . Int J Surg Pathol . 2022;30(2):200-206. Patton A, Bridge JA, Liebner D, et al. A YAP1::TFE3 cutaneous low-grade fibromyxoid neoplasm: a novel entity! Genes Chromosomes Cancer . 2022;61(4):194-199. Campbell K, Bridge JA, DiMaio D, et al. Dermatofibrosarcoma protuberans with platelet-derived growth factor-D rearrangement; two cases with morphologically distinct presentations . J Cutan Pathol . 2022;49(3):274-277. Lindsey MS, Bridge JA, Douglas DS, et al. Primary cutaneous alveolar rhabdomyosarcoma in an elderly adult: a rare potential mimic of Merkel cell carcinoma . Am J Dermatopathol . 2022;44(3):218-222. Cowan B, Klein E, Jansz K, et al. Longitudinal follow-up and performance validation of an mRNA-based urine test (Xpert® Bladder Cancer Monitor) for surveillance in patients with non-muscle-invasive bladder cancer . BJU Int . 2021;128(6):713-721. Kerr DA, Thompson LDR, Tafe LJ, et al. Clinicopathologic and genomic characterization of inflammatory myofibroblastic tumors of the head and neck: highlighting a novel fusion and potential diagnostic pitfall . Am J Surg Pathol . 2021;45(12):1707-1719. Sadaf A, Szabo S, Ferguson K, et al. Novel ARHGAP23-FER fusion in a metastatic spindle cell-predominant neoplasm with a myofibroblastic phenotype and a sustained metabolic response to lorlatinib . Cancer . 2021;127(22):4124-4130. Hughes CE, Correa H, Benedetti DJ, et al. Second report of PDE10A -BRAF fusion in pediatric spindle cell sarcoma with infantile fibrosarcoma-like morphology suggesting PDE10A -BRAF fusion is a recurrent event . Pediatr Dev Pathol . 2021;24(6):554-558. Al-Obaidy KI, Bridge JA, Cheng L, et al. EWSR1-PATZ1 fusion renal cell carcinoma: a recurrent gene fusion characterizing thyroid-like follicular renal cell carcinoma . Mod Pathol . 2021;34(10):1921-1934. Parra O, Bridge JA, Busam KJ, et al. Dermal melanocytic tumor with CRTC1-TRIM11 fusion: Report of two additional cases with review of the literature of an emerging entity . J Cutan Pathol . 2021;48(7):915-924. Wang H, Weiss VL, Hoffman RD, et al. Salivary gland NUT carcinoma with prolonged survival in children: case illustration and systematic review of literature . Head Neck Pathol . 2021;15(1):236-243. Motanagh S, Bridge JA, Linos K. Acral fibromyxoma with loss of Rb1 by immunohistochemistry and fluorescence in situ hybridization: A diagnostically exploitable marker . J Cutan Pathol . 2021;48(2):295-301. Valenberg FJPV, Hiar AM, Wallace E, et al. Validation of an mRNA-based urine test for the detection of bladder cancer in patients with haematuria . Eur Urol Oncol . 2021;4(1):93-101. Pettus JR, Kerr DA, Stan RV, et al. Primary myxoid and epithelioid mesenchymal tumor of the kidney with a novel GLI1-FOXO4 fusion . Genes Chromosomes Cancer . 2021;60(2):116-122. Linos K, Kerr DA, Sumegi J, et al. Pan-Trk immunoexpression in a superficial malignant ossifying fibromyxoid tumor with ZC3H7B-BCOR fusion: a potential obfuscating factor in the era of targeted therapy . J Cutan Pathol . 2021;48(2):340-342. Bridge JA, Sumegi J, Royce T, et al. A novel CLTC-FOSB gene fusion in pseudomyogenic hemangioendothelioma of bone . Genes Chromosomes Cancer . 2021;60(1):38-42. Parra O, Kerr DA, Bridge JA, et al. A case of YAP1 and NUTM1 rearranged porocarcinoma with corresponding immunohistochemical expression: review of recent advances in poroma and porocarcinoma pathogenesis with potential diagnostic utility . J Cutan Pathol . 2021;48(1):95-101.