Elizabeth L. Frank, PhD, MLS(ASCP)CM, DABCC, FADLM

Co-Medical Director: Mass Spectrometry
Professor, University of Utah School of Medicine

Education

• Doctorate Degree—Organic Chemistry, University of Colorado, Boulder
• Internship—Pathology, Penrose Hospital
• Fellowship—Pharmacy, University of Colorado Health Sciences Center
• Fellowship—Clinical Chemistry, University of Utah School of Medicine

Certification/Affiliations

• American Board of Clinical Chemistry
• American Society for Clinical Pathology
• Association for Diagnostics & Laboratory Medicine Academy

Research Interests

• Measurement of biogenic amines, porphyrins, and vitamins using high-performance liquid chromatography and mass spectrometry
• Biochemical assessment of nephrolithiasis risk
• Determination of calculi composition
• Use of vitamin testing to evaluate health status

Recent Publications

• Bergelson I, Walker C, Frank EL, et al. Felbamate urolithiasis. BMJ Case Rep. 2023;16(12):e253883.
• Pandya V, Frank EL. A simple, fast, and reliable LC-MS/MS method for the measurement of homovanillic acid and vanillylmandelic acid in urine specimens. Methods Mol Biol. 2022;2546:175-183.
• Nelson HA, Frank EL. Quantification of 5-hydroxyindoleacetic acid in urine by ultra-performance liquid chromatography tandem mass spectrometry. Methods Mol Biol. 2022;2546:195-204.
• Kushnir MM, Nelson GJ, Frank EL, et al. LC-MS/MS method for high-throughput analysis of methylmalonic acid in serum, plasma, and urine: method for analyzing isomers without chromatographic separation. Methods Mol Biol. 2022;2546:295-309.
• Doyle K, Frank EL. Verifying clinically derived reference intervals for daily excretion rates of fractionated metanephrines using modern indirect reference interval models. Am J Clin Pathol. 2021;156(4):691-699.
• Smy L, Kushnir MM, Frank EL. A high sensitivity LC-MS/MS method for measurement of 3-methoxytyramine in plasma and associations between 3-methoxytyramine, metanephrines, and dopamine. J Mass Spectrom Adv Clin Lab. 2021;21:19-26.
• Anderson KE, Lobo R, Salazar D, et al. Biochemical diagnosis of acute hepatic porphyria: updated expert recommendations for primary care physicians. Am J Med Sci. 2021;362(2):113-121.
• Kushnir MM, Song B, Yang E, et al. Development and clinical evaluation of a high-throughput LC-MS/MS assay for vitamin B6 in human plasma and serum. J Appl Lab Med. 2021;6(3):702-714.