Dharmendra Jain, PhD

Associate Director: Histocompatibility and Immunogenetics Laboratory
Assistant Professor (Clinical), University of Utah School of Medicine

Specialties

• Clinical immunology
• Histocompatibility
• Immunogenetics

Education

• Doctorate—Biotechnology, Amity University Noida
• MS Degree—Biotechnology, Barkatullah Vishwavidyalaya, Bhopal
• BS Degree—Biology, Mohanlal Sukhadia University, Udaipur
• Fellowship—Clinical Immunology, Histocompatibility, and Immunogenetics, University of Utah School of Medicine

Current/Past Roles

• Scientific officer, Oncquest Laboratories, New Delhi, India
• Scientific assistant, SN GeneLab, Surat, India

Certification/Affiliations

• S(ACHI) Certification
• The American College of Histocompatibility and Immunogenetics

Research Interests

• Identifying the role of non-HLA antibodies in solid organ transplantation
• Evaluation of clinical non-HLA testing assays in the context of clinical utility

Awards

• TxDx COP ATC 2023 Travel Grant, American Transplant Congress
• Second Place Award, Fellow Research Grand Rounds, University of Utah, 2022
• Travel Award, American Society for Histocompatibility and Immunogenetics 47th Annual Meeting, 2021
• Doctorate Award, The Association of Medical Laboratory Immunologists 34th Annual Meeting, 2021
• Career Advancement for Postdocs Travel Award, Division of Biological Science, Immunology, 2019
• Poster Award, American Association of Immunologist, 2019
• Mentee-Mentor Award, International Transplantation Science, 2019
• Quality Champion Award, National Accreditation Board for Testing and Calibration Laboratories, Medanta-The Medicity, 2016
• Harold Gunson Fellowship Award, International Society of Blood Transfusion, 2015

Recent Publications

• Durgam SS, Khiew SHW, Sayin I, et al. MHC tetramers specifically identify high- and low-avidity donor-specific B cells in transplantation tolerance and rejection. Transplantation. 2023;107(12):2526-2532.
• Jain D, Pido MTJ, Delgado JC, et al. Comparison of two clinical laboratory assays for measuring serum adalimumab and antibodies to adalimumab. J Appl Lab Med. 2023;8(6):1054-1064.
• Chauhan R, Jain D, Tiwari AK, et al. Laboratory diagnosis of ANCA-associated vasculitis (AAV) using a combination of immunofluorescence test (IIFT) and line immunoassay (LIA): single-centre report from India. Reumatol Clin (Engl Ed). 2022;18(1):15-19.
• Asano Y, Daccache J, Jain D, et al. Innate-like self-reactive B cells infiltrate human renal allografts during transplant rejection. Nat Commun. 2021;12(1):4372.
• Suah AN, Tran DV, Khiew SH, et al. Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice. J Clin Invest. 2021;131(1):e140715.
• Jain D, Rajab A, Young JS, et al. Reversing donor-specific antibody responses and antibody-mediated rejection with bortezomib and belatacept in mice and kidney transplant recipients. Am J Transplant. 2020;20(10):2675-2685.
• Khiew SH, Jain D, Chen J, et al. Transplantation tolerance modifies donor-specific B cell fate to suppress de novo alloreactive B cells. J Clin Invest. 2020;130(7):3453-3466.
• Chauhan R, Jain D, Dorwal P, et al. The incidence of immunofluorescence patterns and specific autoantibodies observed in autoimmune patients in a tertiary care centre. Eur Ann Allergy Clin Immunol. 2019;51(4):165-173.
• Jain D, Choudhuri J, Chauhan R, et al. False negative single antigen bead assay: Is it always an effect of prozone? J Clin Lab Anal. 2018;32(2):e22237.