Maria A. Pletneva, MD, PhD

Associate Professor (Clinical), University of Utah School of Medicine

Specialties

• Gastrointestinal
• Pancreatic pathology
• Hepatic pathology

Education

• Doctorate Degree—Johns Hopkins University School of Medicine
• Medical Degree—Johns Hopkins University School of Medicine
• Residency—Anatomic and Clinical Pathology, University of Michigan Health System
• Fellowship—Hematopathology, University of Michigan Health System
• Fellowship—Surgical Pathology, University of Michigan Health System

Current/Past Roles

• 2015–2016—Senior Staff Pathologist, Henry Ford Hospital, Henry Ford Health System
• 2016–2021—Assistant Professor of Pathology, University of Utah
• 2021–present—Associate Professor of Pathology, University of Utah

Research Interests

• Improvement of diagnostic tools for eosinophilic and mast cell disease
• Improvement of diagnostic tools for graft-versus-host disease

Recent Publications

• Turapov T, Uchida AM, Pletneva MA, et al. Gastrointestinal tissue eosinophil quantification in healthy adult volunteers. Gastroenterology. 2025:S0016-5085(25)00415-9.
• Allen-Brady K, Clayton F, Hazel MW, et al. Overlap of genomic and transcriptomic genes identified in familial eosinophilic esophagitis. Gastroenterology. 2025:S0016-5085(25)00342-7.
• Pyne AL, Uchida AM, Hazel MW, et al. Differing epithelial and immunologic activation patterns following food reintroduction reveal different transcriptional profiles in active eosinophilic esophagitis. Gastroenterology. 2024:S0016-5085(24)05642-7.
• Martin LJ, Zhang X, Chehade M, et al. Long-term durability between parent and child patient reported outcomes in eosinophilic esophagitis. J Allergy Clin Immunol. 2024;154(5):1232-1240.e12.
• Pyne AL, Uchida AM, Hazel MW, et al. Effect of benralizumab on histopathology and inflammatory signatures in a clinical cohort of eosinophilic esophagitis. Dis Esophagus. 2024;38(1):doae031.
• Kim S, Ben-Baruch Morgenstern N, Osonoi K, et al. Nonepithelial gene expression correlates with symptom severity in adults with eosinophilic esophagitis. J Allergy Clin Immunol Pract. 2024;12(12):3346-3355.e1.
• Sato H, Dellon ES, Aceves SS, et al. Clinical and molecular correlates of the Index of Severity for Eosinophilic Esophagitis. J Allergy Clin Immunol. 2024;154(2):375-386.e4.
• Arva NC, Bernieh A, Lopez-Nunez O, et al. Histopathology of eosinophilic gastrointestinal diseases beyond eosinophilic esophagitis. Immunol Allergy Clin North Am. 2024;44(2):369-381.
• Collins MH, Arva NC, Bernieh A, et al. Histopathology of eosinophilic esophagitis. Immunol Allergy Clin North Am. 2024;44(2):205-221.
• Hirano I, Dellon ES, Falk GW, et al. Ascending to new heights for novel therapeutics for eosinophilic esophagitis. Gastroenterology. 2024;166(1):1-10.
• Genta RM, Turner KO, Collins MH, et al. Quantification of mucosal mast cells in the gastrointestinal tract: a primer for practicing pathologists. Arch Pathol Lab Med. 2024;148(2):e25-e35.
• Boylan KE, Kanth P, Delker D, et al. Three pathologic criteria for reproducible diagnosis of colonic sessile serrated lesion versus hyperplastic polyp. Hum Pathol. 2023;137:25-35.
• Talley NJ, Peterson KA, Genta RM, et al. High discovery rate of duodenal and gastric eosinophilia in patients with unexplained moderate-severe abdominal symptoms: a prospective us multisite study. Gastroenterology. 2023;164(4):680-683.e2.
• Arva N, Genta RM, Pletneva M, et al. Eosinophilic gastrointestinal disorders: a new path. Pediatr Dev Pathol. 2022;25(5):568-569.
• Radojcic V, Pletneva M, Lee CJ, et al. Hedgehog blockade in steroid-refractory sclerotic chronic graft-versus-host disease. Br J Haematol. 2021;195(2):e120-e122.
• Eisele Y, Mallea PM, Gigic B, et al. Fusobacterium nucleatum and clinicopathologic features of colorectal cancer: results from the ColoCare Study. Clin Colorectal Cancer. 2021;20(3):e165-e172.