ARUP offers a nucleic acid amplification (NAA) test for the diagnosis of a current COVID-19 infection and an immunoglobulin G (IgG) antibody test (targeting nucleocapsid proteins) for the evaluation of exposure to SARS-CoV-2.
Diagnostic Test
SARS-CoV-2 (COVID-19) by NAA (3002638)
Clinical Use:
Recommended molecular test (NAA) to detect SARS-CoV-2 in symptomatic patients. Because symptoms of COVID-19 are similar to those of other respiratory infections, a clinical evaluation alone is not sufficient to make a COVID-19 diagnosis.
Benefits:
- We offer a rapid turnaround time.
- ARUP’s molecular assays are designed to detect several SARS-CoV-2 RNA gene targets, allowing for the detection of COVID-19 variants.
- We accept multiple specimen types, including nasopharyngeal swabs, oropharyngeal swabs, nasal swabs, and saliva specimens.
Antibody Test
COVID-19 IgG, Qualitative by CIA (3002776)
Clinical Use:
Use for the qualitative detection of IgG antibodies against the nucleocapsid protein of SARS-CoV-2 that develop in response to natural infection with SARS-CoV-2 (COVID-19 infection). These antibodies do not develop as a result of a COVID-19 vaccination.
Benefits:
- Our highly sensitive and specific assay detects low levels of IgG antibodies.
Related Testing
Vaccine-Induced Immune Thrombotic Thrombocytopenia
Unusual thrombotic events with thrombocytopenia have been reported in a small number of patients following receipt of two SARS-CoV-2 vaccines (AstraZeneca and Johnson & Johnson/Janssen). For more information, please refer to the Quick Answers for Clinicians section of the ARUP Consult® Heparin Induced Thrombocytopenia - HIT topic.
Clinical Resources
Testing Guidance
- Infectious Diseases Society of America. Guidelines on the diagnosis of COVID-19: molecular diagnostic testing. Updated Sep 2023; accessed May 2024.
- Recommendations for molecular diagnostic testing
- Infectious Diseases Society of America. Guidelines on the diagnosis of COVID-19: serologic testing. Published Feb 2024; accessed May 2024.
- Recommendations for serologic testing
- Centers for Disease Control and Prevention. Overview of testing for SARS-CoV-2. Updated Jul 2024; accessed Aug 2024.
- Recommendations for viral and antibody testing
ARUP’s COVID-19 assays are offered under FDA Emergency Use Authorization (EUA). Please visit the FDA web page, EUA Authorized Serology Test Performance, for more information.
ARUP Consult
ARUP Consult is a free source of expert guidance on laboratory testing that provides point-of-care diagnostic and interpretive information to clinicians, hospital and laboratory clients, and healthcare providers.
- COVID-19 - SARS-CoV-2 topic