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Laboratory Evaluation of Inflammatory Myopathies
ARUP excels in antibody testing for myositis and associated conditions such as interstitial lung disease. Our test suite uses various methodologies and expert interpretation to provide a complete clinical picture.
New Antibodies
Testing for Ha, Ks, and Zo
Ha, Ks, and Zo antibodies may be useful in diagnosis, prognosis, and disease management for patients with antisynthetase syndrome, a subtype of myositis. ARUP has added these antibodies to our myositis panels.
Why Choose ARUP?
Testing That Fits Your Needs
ARUP offers several myositis-related antibody panels, enabling providers to order testing based on the patient’s clinical characteristics.
Use of Immunoprecipitation
ARUP is one of three clinical laboratories in the United States offering immunoprecipitation. The use of this methodology facilitates validation and discovery of new antibodies.
Testing Curated by Medical Experts
ARUP’s testing includes integrated results interpretation by a medical director. Our panels are built with different assays and methods, providing additional quality control. This increases the sensitivity and specificity of our tests.
Fast Turnaround Time
ARUP’s published turnaround time (TAT) is seven to 18 days, whereas other labs report TATs of 14 to 21 days or six to eight weeks.
ARUP Laboratories Panels for Myositis and Associated Conditions
| Test Name | Test Code | Additional Test Information |
|---|---|---|
| Extended Myositis Panel | 3018867 | Test Fact Sheet |
| Dermatomyositis and Polymyositis Panel | 3018866 | Test Fact Sheet |
| Polymyositis Panel | 3018868 | Test Fact Sheet |
| Dermatomyositis Autoantibody Panel | 3018870 | Test Fact Sheet |
| Interstitial Lung Disease Autoantibody Panel | 3018869 | Test Fact Sheet |
For a comprehensive list of the individual components included in these panels, refer to our ARUP Inflammatory Myopathy Panels Table.
Additional Resources
ARUP Inflammatory Myopathy Panels Table
ARUP Consult Inflammatory Myopathies topic
ARUP Consult Interstitial Lung Disease Consult topic
From the Experts
Luong K, Smith T, Peterson L. Antibodies to Ha, Ks, and Zo: frequency and characteristics of antibody-positive patients in an unselected cohort (P9-11.004). Neurology. 2024;102(17)(Suppl 1).
ARUP Medical Experts
Lisa K. Peterson, PhD, D(ABMLI)
Associate Professor of Pathology (Clinical), University of Utah School of Medicine
Medical Director, Immunology, ARUP Laboratories
Tammy Smith, MD, PhD
Assistant Professor of Neurology, Division of Neuroimmunology, University of Utah School of Medicine
Clinical Consultant, Autoimmune Neurology, ARUP Laboratories
