|
Test Code |
Suspected Diagnosis |
Probe Target |
Gene(s)/Unique Sequence |
|
0040208 |
Aneuploidy, common |
13/18/21/X/Y |
|
Microdeletion Syndromes |
|
2002299 (Order this test and specify probes) |
4p- |
4p16.3 |
WHSC1 |
|
|
5p- |
5p15.2 |
D5S23-D5S721 |
|
|
15q11.2-13 duplication |
15q11.2-13 |
D15S11, D15S10 |
|
|
22qter deletion |
22q13.3 |
22qtel (SHANK3) |
|
|
Angelman syndrome |
15q11.2-13 |
D15S10 |
|
|
Cri-du-chat syndrome |
5p15.2 |
D5S23-D5S721 |
|
|
DiGeorge syndrome |
22q11.2 |
TUPLE-1 (HIRA) |
|
|
Kallmann syndrome |
Xp22.3 |
KAL1 |
|
|
Male detection (SRY) |
Yp11.3 |
SRY |
|
|
Miller-Dieker syndrome (lissencephaly) |
17p13.3 |
LIS1 |
|
|
Phelan-McDermid syndrome |
22q13.3 |
22qtel (SHANK3) |
|
|
Prader-Willi syndrome |
15q11.2-13 |
D15S10 |
|
|
SHOX |
Xp22.3 |
SHOX |
|
|
Smith-Magenis syndrome |
17p11.2 |
SHMT1, TOP3, FL11, LLGL1 |
|
|
SRY |
Yp11.3 |
SRY |
|
|
Steroid sulfatase deficiency (STS, X-linked ichthyosis) |
Xp22.3 |
STS |
|
|
Velocardiofacial (VCF) syndrome |
22q11.2 |
TUPLE-1 (HIRA) |
|
|
Williams syndrome (elastin) |
7q11.23 |
ELN, LIMK1, D7S613 |
|
|
Wolf-Hirschhorn syndrome |
4p16.3 |
WHSC1 |
Miscellaneous (Please contact the lab prior to ordering) |
|
2002299 or 2002298 (Order one of these tests and specify probes) |
Acrocentric p-arm |
|
NOR regions of all acrocentric chromosomes |
|
|
X centromere |
Xcen |
DXZ1 |
|
|
X inactivation locus |
Xq13 |
XIST |
|
|
Y centromere |
Ycen |
DYZ3 |
|
|
Male detection (SRY) |
Yp11.3 |
SRY |
|
|
Yq12 |
Yq12 |
DYZ1-YsatIII |