Oncology Studies, FISH Probes—Bone Marrow and Whole Blood

To order individual probes, use ARUP test code 2002298, Chromosome, FISH Interphase, and specify the desired probe(s). Testing provided by the ARUP Cytogenetics Laboratory

Test # Test Name/DescriptionDisease SubtypeProbe TargetGene(s)/Unique Sequence
2002647Acute Lymphoblastic Leukemia Panel (ALL) by FISH, Adult 8q24MYC
   t(9;22)(q34;q11.2)BCR-ABL1
   11q23KMT2A (MLL)
   14q32IGH
   19p13TCF3 (E2A)
2002719Acute Lymphoblastic Leukemia Panel (ALL), Pediatric +4,+10CEP4, CEP10
   t(9;22)(q34;q11.2)BCR-ABL1
   11q23KMT2A (MLL)
   t(12;21)(p13;q22)ETV6-RUNX1 (TEL-AML1)
3016654Acute Myeloid Leukemia Panel by FISH t(15;17)(q24;q21)PML-RARA
   t(8;21)(q22;q22)RUNX1T1-RUNX1 (ETO-AML1)
   inv(16)(p13.3q22)
or
t(16;16)(p13.1;q22)     		CBFB-MYH11
   11q23KMT2A (MLL)
   inv(3) or t(3;3)RPN1/MECOM (EVI1)
   del(5)(q31)EGR1
   del(7)(q31)/-7D7S486
   11p15NUP98
2002653Acute Myelogenous Leukemia (AML) with Myelodysplastic Syndrome (MDS) or Therapy-Related AML, by FISH del(5)(q31)EGR1
   del(7)(q31)/-7D7S486
   11q23KMT2A (MLL)
2002298Chromosome FISH, Interphase
(Alveolar rhabdomyosarcoma probes ordered individually as test code 2002298)		 13q13FKHR (FOX01)
2002295Chromosome FISH, CLL Panel del(11)(q22.3)ATM
   +12D12Z3
   del(13)(q14.3)D13S319
   del(17)(p13.1)TP53 (p53)
2002298Chromosome FISH, Interphase (Chronic myelogenous leukemia [CML] probes ordered individually as test code 2002298) t(9;22)(q34;q11.2)BCR-ABL1, ASS1
2002378Eosinophilia Panel by FISH 4q12PDGFRA-CHIC2-FIP1L1
   5q32PDGFRB
   8p12FGFR1
2002650Lymphoma (Aggressive) Panel by FISH 3q27BCL6
   8q24MYC
   t(14;18)(q32;q21)IGH-BCL2
2002298Chromosome FISH, Interphase (Lymphoma probes ordered individually as test code 2002298)Burkitt8q24MYC
  Diffuse large cell3q27BCL6
  Folliculart(14;18)(q32;q21)IGH-BCL2
  IgH rearrangement14q32IGH
  Mantle cellt(11;14)(q13;q32)IGH-CCND1
  MALT18q21MALT1
3002063Multiple Myeloma Panel by FISH 1q21CKS1B
   +9/9pJAK2
   t(11;14)(q13;q32)IGH-CCND1
   t(14;20)(q32;q12)IGH-MAFB
   del(17)(p13)TP53 (p53)
   t(4;14)(p16;q32)IGH-FGFR3 and MMSET
   t(14;16)(q32;q23)IGH-MAF
2002709Myelodysplastic Syndrome (MDS) Panel by FISH del(5)(q31)EGR1
   del(7)(q31)/-7D7S486
   +8CEP8
   del(20)(q12)D20S108
2002360Myeloproliferative Disorders Panel by FISH 4q12PDGFRA-CHIC2-FIP1L1
   5q32PDGFRB
   8p12FGFR1
   t(9;22)(q34;q11.2)BCR-ABL1
2002298Chromosome FISH, Interphase (Myxoid liposarcoma probes ordered individually as test code 2002298) 12q13DDIT3 (CHOP)
3000455Ph-Like Acute Lymphoblastic Leukemia (ALL) Panel by FISH Xp22.33/Yp11.32CRLF2
   9p24JAK2
   19p13.2EPOR
   5q32CSF1R
   9q34.1ABL1
   1q25.2ABL2
   5q32PDGFRB
2002298Chromosome FISH, Interphase (Sarcoma probes ordered individually as test code 2002298)Synovial18q11.2SS18 (SYT)
  Ewing22q12.2EWSR1
 
Oncology Studies, FISH—Paraffin Block
30013091p/19q Deletion by FISH   
3001495Aggressive B-Cell Lymphoma Reflex Panel by FISH, Tissue   
3001302ALK Gene Rearrangements by FISH, Lung   
3001311BCL6 (3q27) Gene Rearrangement by FISH   
3001304 DDIT3 (CHOP) (12q13) Gene Rearrangement by FISH   
3001310 EGFR Gene Amplification by FISH   
2008603ERBB2 (HER-2/neu) Gene Amplification by FISH with Reflex, Tissue   
3001305 EWSR1 (22q12) Gene Rearrangement by FISH   
3001297 FOXO1 (FKHR) (13q14) Gene Rearrangement by FISH   
3000548FUS (16p11) Gene Rearrangement by FISH   
3001298IGH-BCL2 Fusion, t(14;18) by FISH (for the detection of follicular lymphoma)   
3001306 IGH-CCND1 Fusion, t(11;14) by FISH   
3001299 IGH-MYC Fusion t(8;14) by FISH   
3001568IRF4/DUSP22 (6p25) Gene Rearrangement by FISH   
3001313 MET Gene Amplification by FISH   
3001301 MDM2 Gene Amplification by FISH   
3001300 MYC(8q24) Gene Rearrangement by FISH   
3001307MYCN (N-MYC) Gene Amplification by FISH   
3001312RET Gene Rearrangements by FISH   
3001308ROS1 by FISH   
3001303 SS18 (SYT) (18q11) Gene Rearrangement by FISH   
 
Oncology Studies, FISH—Other
2002528Pancreatobiliary FISH